Jarman M - Search Results

1

The 16,17-double bond is needed for irreversible inhibition of human cytochrome p45017alpha by abiraterone (17-(3-pyridyl)androsta-5, 16-dien-3beta-ol) and related steroidal inhibitors.

Jarman M, Barrie SE, Llera JM. Jarman M, et al. J Med Chem. 1998 Dec 31;41(27):5375-81. doi: 10.1021/jm981017j. J Med Chem. 1998. PMID: 9876107

2

Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis.

Jarman M, Barrie SE, Deadman JJ, Houghton J, McCague R, Rowlands MG. Jarman M, et al. J Med Chem. 1990 Sep;33(9):2452-5. doi: 10.1021/jm00171a019. J Med Chem. 1990. PMID: 2391687

3

Esters of 3-pyridylacetic acid that combine potent inhibition of 17 alpha-hydroxylase/C17,20-lyase (cytochrome P45017 alpha) with resistance to esterase hydrolysis.

Rowlands MG, Barrie SE, Chan F, Houghton J, Jarman M, McCague R, Potter GA. Rowlands MG, et al. Among authors: jarman m. J Med Chem. 1995 Oct 13;38(21):4191-7. doi: 10.1021/jm00021a008. J Med Chem. 1995. PMID: 7473546

4

Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer.

Potter GA, Barrie SE, Jarman M, Rowlands MG. Potter GA, et al. Among authors: jarman m. J Med Chem. 1995 Jun 23;38(13):2463-71. doi: 10.1021/jm00013a022. J Med Chem. 1995. PMID: 7608911

5

Pharmacology of novel steroidal inhibitors of cytochrome P450(17) alpha (17 alpha-hydroxylase/C17-20 lyase).

Barrie SE, Potter GA, Goddard PM, Haynes BP, Dowsett M, Jarman M. Barrie SE, et al. Among authors: jarman m. J Steroid Biochem Mol Biol. 1994 Sep;50(5-6):267-73. doi: 10.1016/0960-0760(94)90131-7. J Steroid Biochem Mol Biol. 1994. PMID: 7918112

6

3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancer.

Chan FC, Potter GA, Barrie SE, Haynes BP, Rowlands MG, Houghton J, Jarman M. Chan FC, et al. Among authors: jarman m. J Med Chem. 1996 Aug 16;39(17):3319-23. doi: 10.1021/jm950749y. J Med Chem. 1996. PMID: 8765515

7

Biochemistry and pharmacokinetics of potent non-steroidal cytochrome P450(17alpha) inhibitors.

Barrie SE, Haynes BP, Potter GA, Chan FC, Goddard PM, Dowsett M, Jarman M. Barrie SE, et al. Among authors: jarman m. J Steroid Biochem Mol Biol. 1997 Mar;60(5-6):347-51. doi: 10.1016/s0960-0760(96)00225-7. J Steroid Biochem Mol Biol. 1997. PMID: 9219927

8

Inhibition of 17 alpha-hydroxylase/C17-C20 lyase by bifluranol and its analogues.

Barrie SE, Rowlands MG, Foster AB, Jarman M. Barrie SE, et al. Among authors: jarman m. J Steroid Biochem. 1989 Dec;33(6):1191-5. doi: 10.1016/0022-4731(89)90429-9. J Steroid Biochem. 1989. PMID: 2559252

9

Selective inhibition of cholesterol side-chain cleavage by potential pro-drug forms of aminoglutethimide.

Jarman M, Barrie SE, Leung CS, Rowlands MG. Jarman M, et al. Anticancer Drug Des. 1988 Dec;3(3):185-90. Anticancer Drug Des. 1988. PMID: 3264700

10

Evaluation of some 4-fluoro- and 4-cyano derivatives of delta 4,3-ketosteroids as inhibitors of testosterone 5 alpha-reductase.

Jarman M, Barrie SE, Houghton J, Rowlands MG, Mann J, Haase-Held M, Hatzis M. Jarman M, et al. J Enzyme Inhib. 1994;8(1):17-23. doi: 10.3109/14756369409040773. J Enzyme Inhib. 1994. PMID: 7539066

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