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Page 1
ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut.
Lyu M, Suzuki H, Kang L, Gaspal F, Zhou W, Goc J, Zhou L, Zhou J, Zhang W; JRI Live Cell Bank; Shen Z, Fox JG, Sockolow RE, Laufer TM, Fan Y, Eberl G, Withers DR, Sonnenberg GF. Lyu M, et al. Nature. 2022 Oct;610(7933):744-751. doi: 10.1038/s41586-022-05141-x. Epub 2022 Sep 7. Nature. 2022. PMID: 36071169 Free PMC article.
In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue.
Li Z, Tuong ZK, Dean I, Willis C, Gaspal F, Fiancette R, Idris S, Kennedy B, Ferdinand JR, Peñalver A, Cabantous M, Murtuza Baker S, Fry JW, Carlesso G, Hammond SA, Dovedi SJ, Hepworth MR, Clatworthy MR, Withers DR. Li Z, et al. J Exp Med. 2022 Jun 6;219(6):e20210749. doi: 10.1084/jem.20210749. Epub 2022 Apr 26. J Exp Med. 2022. PMID: 35472220 Free PMC article.
Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3.
Tachó-Piñot R, Stamper CT, King JI, Matei-Rascu V, Richardson E, Li Z, Roberts LB, Bassett JW, Melo-Gonzalez F, Fiancette R, Lin IH, Dent A, Harada Y, Finlay C, Mjösberg J, Withers DR, Hepworth MR. Tachó-Piñot R, et al. Cell Rep. 2023 Nov 28;42(11):113425. doi: 10.1016/j.celrep.2023.113425. Epub 2023 Nov 10. Cell Rep. 2023. PMID: 37950867 Free PMC article.
ILC killer: Qu'est-ce que c'est?
Withers DR, Hepworth MR. Withers DR, et al. Sci Immunol. 2022 Apr 8;7(70):eabo2159. doi: 10.1126/sciimmunol.abo2159. Epub 2022 Apr 8. Sci Immunol. 2022. PMID: 35394813 Review.
Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.
Halim TYF, Rana BMJ, Walker JA, Kerscher B, Knolle MD, Jolin HE, Serrao EM, Haim-Vilmovsky L, Teichmann SA, Rodewald HR, Botto M, Vyse TJ, Fallon PG, Li Z, Withers DR, McKenzie ANJ. Halim TYF, et al. Immunity. 2018 Jun 19;48(6):1195-1207.e6. doi: 10.1016/j.immuni.2018.05.003. Epub 2018 Jun 12. Immunity. 2018. PMID: 29907525 Free PMC article.
Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis.
Castellanos JG, Woo V, Viladomiu M, Putzel G, Lima S, Diehl GE, Marderstein AR, Gandara J, Perez AR, Withers DR, Targan SR, Shih DQ, Scherl EJ, Longman RS. Castellanos JG, et al. Immunity. 2018 Dec 18;49(6):1077-1089.e5. doi: 10.1016/j.immuni.2018.10.014. Epub 2018 Dec 11. Immunity. 2018. PMID: 30552020 Free PMC article.
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