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MICU1 motifs define mitochondrial calcium uniporter binding and activity.
Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M. Hoffman NE, et al. Cell Rep. 2013 Dec 26;5(6):1576-1588. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12. Cell Rep. 2013. PMID: 24332854 Free PMC article.
S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.
Hawkins BJ, Irrinki KM, Mallilankaraman K, Lien YC, Wang Y, Bhanumathy CD, Subbiah R, Ritchie MF, Soboloff J, Baba Y, Kurosaki T, Joseph SK, Gill DL, Madesh M. Hawkins BJ, et al. J Cell Biol. 2010 Aug 9;190(3):391-405. doi: 10.1083/jcb.201004152. Epub 2010 Aug 2. J Cell Biol. 2010. PMID: 20679432 Free PMC article.
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M. Mallilankaraman K, et al. Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25. Nat Cell Biol. 2012. PMID: 23178883 Free PMC article.