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Rapid detection of mouse spermatogenic defects by testicular cellular composition analysis via enhanced deep learning model.
Ao N, Zang M, Lu Y, Jiao Y, Lu H, Cai C, Wang X, Li X, Xie M, Zhao T, Xu J, Xu EY. Ao N, et al. Andrology. 2024 Oct 7. doi: 10.1111/andr.13773. Online ahead of print. Andrology. 2024. PMID: 39375288
OBJECTIVES: Establish an expeditious histopathological analysis of mutant mice testicular sections stained with commonly available hematoxylin and eosin (H&E) via enhanced deep learning model MATERIALS AND METHODS: Automated segmentation and cellular composition analysis on t …
OBJECTIVES: Establish an expeditious histopathological analysis of mutant mice testicular sections stained with commonly available hematoxyl …
Intracellular Redox Environment Determines Cancer-normal Cell Selectivity of Selenium Nanoclusters.
Xiong Z, He L, Pi F, Yu Y, Xiao Z, Chen T. Xiong Z, et al. Angew Chem Int Ed Engl. 2024 Oct 14:e202416006. doi: 10.1002/anie.202416006. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39400451
Intracellular redox environments originating from cell metabolism are key factors affecting internalized drug efficacy. Herein, we engineer Se-Se/Se-S bond to assemble selenium (Se) nanoclusters (SeClus) with intracellular redox environment-driven selective structure. Chem …
Intracellular redox environments originating from cell metabolism are key factors affecting internalized drug efficacy. Herein, we en …