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2021 2
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2024 2

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DNA methylation GrimAge version 2.
Lu AT, Binder AM, Zhang J, Yan Q, Reiner AP, Cox SR, Corley J, Harris SE, Kuo PL, Moore AZ, Bandinelli S, Stewart JD, Wang C, Hamlat EJ, Epel ES, Schwartz JD, Whitsel EA, Correa A, Ferrucci L, Marioni RE, Horvath S. Lu AT, et al. Aging (Albany NY). 2022 Dec 14;14(23):9484-9549. doi: 10.18632/aging.204434. Epub 2022 Dec 14. Aging (Albany NY). 2022. PMID: 36516495 Free PMC article.
Epigenetic scores for the circulating proteome as tools for disease prediction.
Gadd DA, Hillary RF, McCartney DL, Zaghlool SB, Stevenson AJ, Cheng Y, Fawns-Ritchie C, Nangle C, Campbell A, Flaig R, Harris SE, Walker RM, Shi L, Tucker-Drob EM, Gieger C, Peters A, Waldenberger M, Graumann J, McRae AF, Deary IJ, Porteous DJ, Hayward C, Visscher PM, Cox SR, Evans KL, McIntosh AM, Suhre K, Marioni RE. Gadd DA, et al. Elife. 2022 Jan 13;11:e71802. doi: 10.7554/eLife.71802. Elife. 2022. PMID: 35023833 Free PMC article.
Genetic variants associated with longitudinal changes in brain structure across the lifespan.
Brouwer RM, Klein M, Grasby KL, Schnack HG, Jahanshad N, Teeuw J, Thomopoulos SI, Sprooten E, Franz CE, Gogtay N, Kremen WS, Panizzon MS, Olde Loohuis LM, Whelan CD, Aghajani M, Alloza C, Alnæs D, Artiges E, Ayesa-Arriola R, Barker GJ, Bastin ME, Blok E, Bøen E, Breukelaar IA, Bright JK, Buimer EEL, Bülow R, Cannon DM, Ciufolini S, Crossley NA, Damatac CG, Dazzan P, de Mol CL, de Zwarte SMC, Desrivières S, Díaz-Caneja CM, Doan NT, Dohm K, Fröhner JH, Goltermann J, Grigis A, Grotegerd D, Han LKM, Harris MA, Hartman CA, Heany SJ, Heindel W, Heslenfeld DJ, Hohmann S, Ittermann B, Jansen PR, Janssen J, Jia T, Jiang J, Jockwitz C, Karali T, Keeser D, Koevoets MGJC, Lenroot RK, Malchow B, Mandl RCW, Medel V, Meinert S, Morgan CA, Mühleisen TW, Nabulsi L, Opel N, de la Foz VO, Overs BJ, Paillère Martinot ML, Redlich R, Marques TR, Repple J, Roberts G, Roshchupkin GV, Setiaman N, Shumskaya E, Stein F, Sudre G, Takahashi S, Thalamuthu A, Tordesillas-Gutiérrez D, van der Lugt A, van Haren NEM, Wardlaw JM, Wen W, Westeneng HJ, Wittfeld K, Zhu AH, Zugman A, Armstrong NJ, Bonfiglio G, Bralten J, Dalvie S, Davies G, Di Forti M, Ding L, Donohoe G, Forstner AJ, Gonzalez-Peñas J, Guimaraes JPOFT, … See abstract for full author list ➔ Brouwer RM, et al. Nat Neurosci. 2022 Apr;25(4):421-432. doi: 10.1038/s41593-022-01042-4. Epub 2022 Apr 5. Nat Neurosci. 2022. PMID: 35383335 Free PMC article.
Epigenetic scores of blood-based proteins as biomarkers of general cognitive function and brain health.
Smith HM, Moodie JE, Monterrubio-Gómez K, Gadd DA, Hillary RF, Chybowska AD, McCartney DL, Campbell A, Redmond P, Page D, Taylor A, Corley J, Harris SE, Valdés Hernández M, Muñoz Maniega S, Bastin ME, Wardlaw JM, Deary IJ, Boardman JP, Mullin DS, Russ TC, Cox SR, Marioni RE. Smith HM, et al. Clin Epigenetics. 2024 Mar 25;16(1):46. doi: 10.1186/s13148-024-01661-7. Clin Epigenetics. 2024. PMID: 38528588 Free PMC article.
Refining epigenetic prediction of chronological and biological age.
Bernabeu E, McCartney DL, Gadd DA, Hillary RF, Lu AT, Murphy L, Wrobel N, Campbell A, Harris SE, Liewald D, Hayward C, Sudlow C, Cox SR, Evans KL, Horvath S, McIntosh AM, Robinson MR, Vallejos CA, Marioni RE. Bernabeu E, et al. Genome Med. 2023 Feb 28;15(1):12. doi: 10.1186/s13073-023-01161-y. Genome Med. 2023. PMID: 36855161 Free PMC article.
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Robertson NA, Latorre-Crespo E, Terradas-Terradas M, Lemos-Portela J, Purcell AC, Livesey BJ, Hillary RF, Murphy L, Fawkes A, MacGillivray L, Copland M, Marioni RE, Marsh JA, Harris SE, Cox SR, Deary IJ, Schumacher LJ, Kirschner K, Chandra T. Robertson NA, et al. Nat Med. 2022 Jul;28(7):1439-1446. doi: 10.1038/s41591-022-01883-3. Epub 2022 Jul 4. Nat Med. 2022. PMID: 35788175 Free PMC article.
Synaptic resilience is associated with maintained cognition during ageing.
King D, Holt K, Toombs J, He X, Dando O, Okely JA, Tzioras M, Rose J, Gunn C, Correia A, Montero C, McAlister H, Tulloch J, Lamont D, Taylor AM, Harris SE, Redmond P, Cox SR, Henstridge CM, Deary IJ, Smith C, Spires-Jones TL. King D, et al. Alzheimers Dement. 2023 Jun;19(6):2560-2574. doi: 10.1002/alz.12894. Epub 2022 Dec 22. Alzheimers Dement. 2023. PMID: 36547260 Free PMC article.
Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health.
Gadd DA, Hillary RF, McCartney DL, Shi L, Stolicyn A, Robertson NA, Walker RM, McGeachan RI, Campbell A, Xueyi S, Barbu MC, Green C, Morris SW, Harris MA, Backhouse EV, Wardlaw JM, Steele JD, Oyarzún DA, Muniz-Terrera G, Ritchie C, Nevado-Holgado A, Chandra T, Hayward C, Evans KL, Porteous DJ, Cox SR, Whalley HC, McIntosh AM, Marioni RE. Gadd DA, et al. Nat Commun. 2022 Aug 9;13(1):4670. doi: 10.1038/s41467-022-32319-8. Nat Commun. 2022. PMID: 35945220 Free PMC article.
23 results