75N93019C00040/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	1
2022	3
2023	2
2024	2

1

Human B Cell Epitope Map of the Lyme Disease Vaccine Antigen, OspA.

Haque HME, Ejemel M, Vance DJ, Willsey G, Rudolph MJ, Cavacini LA, Wang Y, Mantis NJ, Weis DD. Haque HME, et al. ACS Infect Dis. 2022 Dec 9;8(12):2515-2528. doi: 10.1021/acsinfecdis.2c00346. Epub 2022 Nov 9. ACS Infect Dis. 2022. PMID: 36350351

2

Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi.

Rudolph MJ, Davis SA, Haque HME, Ejemel M, Cavacini LA, Vance DJ, Willsey GG, Piazza CL, Weis DD, Wang Y, Mantis NJ. Rudolph MJ, et al. Proteins. 2023 Nov;91(11):1463-1470. doi: 10.1002/prot.26549. Epub 2023 Jul 16. Proteins. 2023. PMID: 37455569 Free PMC article.

3

Single-domain antibodies reveal unique borrelicidal epitopes on the Lyme disease vaccine antigen, outer surface protein A (OspA).

Vance DJ, Basir S, Piazza CL, Willsey GG, Haque HME, Tremblay JM, Rudolph MJ, Muriuki B, Cavacini L, Weis DD, Shoemaker CB, Mantis NJ. Vance DJ, et al. Infect Immun. 2024 Apr 9;92(4):e0008424. doi: 10.1128/iai.00084-24. Epub 2024 Mar 12. Infect Immun. 2024. PMID: 38470113 Free PMC article.

4

Agglutination of Borreliella burgdorferi by Transmission-Blocking OspA Monoclonal Antibodies and Monovalent Fab Fragments.

Frye AM, Ejemel M, Cavacini L, Wang Y, Rudolph MJ, Song R, Mantis NJ. Frye AM, et al. Infect Immun. 2022 Sep 15;90(9):e0030622. doi: 10.1128/iai.00306-22. Epub 2022 Aug 24. Infect Immun. 2022. PMID: 36000876 Free PMC article.

5

Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.

Rudolph MJ, Davis SA, Haque HME, Weis DD, Vance DJ, Piazza CL, Ejemel M, Cavacini L, Wang Y, Mbow ML, Gilmore RD, Mantis NJ. Rudolph MJ, et al. mBio. 2023 Apr 25;14(2):e0298122. doi: 10.1128/mbio.02981-22. Epub 2023 Mar 28. mBio. 2023. PMID: 36976016 Free PMC article.

6

Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody.

Schiller ZA, Rudolph MJ, Toomey JR, Ejemel M, LaRochelle A, Davis SA, Lambert HS, Kern A, Tardo AC, Souders CA, Peterson E, Cannon RD, Ganesa C, Fazio F, Mantis NJ, Cavacini LA, Sullivan-Bolyai J, Hu LT, Embers ME, Klempner MS, Wang Y. Schiller ZA, et al. J Clin Invest. 2021 Jun 1;131(11):e144843. doi: 10.1172/JCI144843. J Clin Invest. 2021. PMID: 33914704 Free PMC article.

7

The Factor H-Binding Site of CspZ as a Protective Target against Multistrain, Tick-Transmitted Lyme Disease.

Marcinkiewicz AL, Lieknina I, Yang X, Lederman PL, Hart TM, Yates J, Chen WH, Bottazzi ME, Mantis NJ, Kraiczy P, Pal U, Tars K, Lin YP. Marcinkiewicz AL, et al. Infect Immun. 2020 Apr 20;88(5):e00956-19. doi: 10.1128/IAI.00956-19. Print 2020 Apr 20. Infect Immun. 2020. PMID: 32122944 Free PMC article.

8

Serological Analysis Identifies Consequential B Cell Epitopes on the Flexible Linker and C-Terminus of Decorin Binding Protein A (DbpA) from Borrelia burgdorferi.

Movahed E, Vance DJ, Ehrbar D, Van Slyke G, Yates J, Kullas K, Rudolph M, Mantis NJ. Movahed E, et al. mSphere. 2022 Aug 31;7(4):e0025222. doi: 10.1128/msphere.00252-22. Epub 2022 Jul 25. mSphere. 2022. PMID: 35876530 Free PMC article.

9

Structure of a Human Monoclonal Antibody in Complex with Outer Surface Protein C of the Lyme Disease Spirochete, Borreliella burgdorferi.

Rudolph MJ, Chen Y, Vorauer C, Vance DJ, Piazza CL, Willsey GG, McCarthy K, Muriuki B, Cavacini LA, Guttman M, Mantis NJ. Rudolph MJ, et al. J Immunol. 2024 Oct 15;213(8):1234-1243. doi: 10.4049/jimmunol.2400247. J Immunol. 2024. PMID: 39240158

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