AG33568/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	2
2012	3
2013	4
2014	1
2015	1
2024	0

1

Transcriptional regulation of β-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments.

Chu J, Zhuo JM, Praticò D. Chu J, et al. Ann Neurol. 2012 Jan;71(1):57-67. doi: 10.1002/ana.22625. Ann Neurol. 2012. PMID: 22275252 Free PMC article.

2

Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice.

Chu J, Giannopoulos PF, Ceballos-Diaz C, Golde TE, Pratico D. Chu J, et al. Mol Neurodegener. 2012 Jan 5;7(1):1. doi: 10.1186/1750-1326-7-1. Mol Neurodegener. 2012. PMID: 22222029 Free PMC article.

3

The involvement of 5-lipoxygenase activating protein in anxiety-like behavior.

Joshi YB, Praticò D. Joshi YB, et al. J Psychiatr Res. 2013 May;47(5):694-8. doi: 10.1016/j.jpsychires.2012.12.011. Epub 2013 Jan 26. J Psychiatr Res. 2013. PMID: 23357209 Free PMC article. Clinical Trial.

4

Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.

Joshi YB, Chu J, Praticò D. Joshi YB, et al. Aging Cell. 2013 Aug;12(4):706-11. doi: 10.1111/acel.12096. Epub 2013 Jun 11. Aging Cell. 2013. PMID: 23634895 Free PMC article.

5

The influence of 5-lipoxygenase on Alzheimer's disease-related tau pathology: in vivo and in vitro evidence.

Chu J, Li JG, Ceballos-Diaz C, Golde T, Praticò D. Chu J, et al. Biol Psychiatry. 2013 Sep 1;74(5):321-8. doi: 10.1016/j.biopsych.2012.12.012. Epub 2013 Jan 23. Biol Psychiatry. 2013. PMID: 23352590 Free PMC article.

6

Knockout of 5-lipoxygenase results in age-dependent anxiety-like behavior in female mice.

Joshi YB, Praticò D. Joshi YB, et al. PLoS One. 2011;6(12):e29448. doi: 10.1371/journal.pone.0029448. Epub 2011 Dec 29. PLoS One. 2011. PMID: 22220211 Free PMC article.

7

Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.

Chu J, Li JG, Hoffman NE, Stough AM, Madesh M, Praticò D. Chu J, et al. Sci Rep. 2015 Jun 16;5:11086. doi: 10.1038/srep11086. Sci Rep. 2015. PMID: 26076991 Free PMC article.

8

Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.

Chu J, Li JG, Praticò D. Chu J, et al. PLoS One. 2013 Aug 7;8(8):e70991. doi: 10.1371/journal.pone.0070991. eCollection 2013. PLoS One. 2013. PMID: 23951061 Free PMC article.

9

5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease.

Chu J, Giannopoulos PF, Ceballos-Diaz C, Golde TE, Praticò D. Chu J, et al. Ann Neurol. 2012 Sep;72(3):442-54. doi: 10.1002/ana.23642. Ann Neurol. 2012. Retraction in: Ann Neurol. 2024 May;95(5):1015. doi: 10.1002/ana.26938. PMID: 23034916 Free PMC article. Retracted.

10

Absence of ALOX5 gene prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease.

Joshi YB, Giannopoulos PF, Chu J, Sperow M, Kirby LG, Abood ME, Praticò D. Joshi YB, et al. Hum Mol Genet. 2014 Dec 20;23(25):6894-902. doi: 10.1093/hmg/ddu412. Epub 2014 Aug 13. Hum Mol Genet. 2014. Retraction in: Hum Mol Genet. 2024 Aug 15:ddae114. doi: 10.1093/hmg/ddae114. PMID: 25122659 Free PMC article. Retracted.

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