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Antibodies in HIV-1 vaccine development and therapy.
Klein F, Mouquet H, Dosenovic P, Scheid JF, Scharf L, Nussenzweig MC. Klein F, et al. Science. 2013 Sep 13;341(6151):1199-204. doi: 10.1126/science.1241144. Science. 2013. PMID: 24031012 Free PMC article. Review.
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants.
Klein F, Nogueira L, Nishimura Y, Phad G, West AP Jr, Halper-Stromberg A, Horwitz JA, Gazumyan A, Liu C, Eisenreich TR, Lehmann C, Fätkenheuer G, Williams C, Shingai M, Martin MA, Bjorkman PJ, Seaman MS, Zolla-Pazner S, Karlsson Hedestam GB, Nussenzweig MC. Klein F, et al. J Exp Med. 2014 Nov 17;211(12):2361-72. doi: 10.1084/jem.20141050. Epub 2014 Nov 10. J Exp Med. 2014. PMID: 25385756 Free PMC article.
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice.
Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, Malbec M, Gravemann S, Billerbeck E, Dorner M, Büning H, Schwartz O, Knops E, Kaiser R, Seaman MS, Wilson JM, Rice CM, Ploss A, Bjorkman PJ, Klein F, Nussenzweig MC. Horwitz JA, et al. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16538-43. doi: 10.1073/pnas.1315295110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043801 Free PMC article.