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Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV.
Van Rompay KK, Abel K, Lawson JR, Singh RP, Schmidt KA, Evans T, Earl P, Harvey D, Franchini G, Tartaglia J, Montefiori D, Hattangadi S, Moss B, Marthas ML. Van Rompay KK, et al. J Acquir Immune Defic Syndr. 2005 Feb 1;38(2):124-34. doi: 10.1097/00126334-200502010-00002. J Acquir Immune Defic Syndr. 2005. PMID: 15671796
Simian immunodeficiency virus (SIV) envelope quasispecies transmission and evolution in infant rhesus macaques after oral challenge with uncloned SIVmac251: increased diversity is associated with neutralizing antibodies and improved survival in previously immunized animals.
Greenier JL, Van Rompay KK, Montefiori D, Earl P, Moss B, Marthas ML. Greenier JL, et al. Virol J. 2005 Feb 14;2:11. doi: 10.1186/1743-422X-2-11. Virol J. 2005. PMID: 15710048 Free PMC article.