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Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol. 2022 Jul 15;7(73):eabm3723. doi: 10.1126/sciimmunol.abm3723. Epub 2022 Jul 8.
Sci Immunol. 2022.
PMID: 35857577
Immunological Methods to Study Monoclonal Antibody Activity in Chronic Lymphocytic Leukaemia.
Carter MJ, Dahal LN, Cleary KLS, Marshall MJE, French RR, Beers SA, Cragg MS.
Carter MJ, et al.
Methods Mol Biol. 2019;1881:173-184. doi: 10.1007/978-1-4939-8876-1_14.
Methods Mol Biol. 2019.
PMID: 30350206
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Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies.
Yu X, Chan HTC, Orr CM, Dadas O, Booth SG, Dahal LN, Penfold CA, O'Brien L, Mockridge CI, French RR, Duriez P, Douglas LR, Pearson AR, Cragg MS, Tews I, Glennie MJ, White AL.
Yu X, et al.
Cancer Cell. 2018 Apr 9;33(4):664-675.e4. doi: 10.1016/j.ccell.2018.02.009. Epub 2018 Mar 22.
Cancer Cell. 2018.
PMID: 29576376
Free PMC article.
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