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Immunological mechanisms of the antitumor effects of supplemental oxygenation.
Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, Podack ER, Ohta A, Sitkovsky MV. Hatfield SM, et al. Sci Transl Med. 2015 Mar 4;7(277):277ra30. doi: 10.1126/scitranslmed.aaa1260. Sci Transl Med. 2015. PMID: 25739764 Free PMC article.
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection.
Hatfield SM, Kjaergaard J, Lukashev D, Belikoff B, Schreiber TH, Sethumadhavan S, Abbott R, Philbrook P, Thayer M, Shujia D, Rodig S, Kutok JL, Ren J, Ohta A, Podack ER, Karger B, Jackson EK, Sitkovsky M. Hatfield SM, et al. J Mol Med (Berl). 2014 Dec;92(12):1283-92. doi: 10.1007/s00109-014-1189-3. Epub 2014 Aug 15. J Mol Med (Berl). 2014. PMID: 25120128 Free PMC article.