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Page 1
Targeting hedgehog in hematologic malignancy.
Irvine DA, Copland M. Irvine DA, et al. Blood. 2012 Mar 8;119(10):2196-204. doi: 10.1182/blood-2011-10-383752. Epub 2012 Jan 5. Blood. 2012. PMID: 22223823 Free article. Review.
CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.
Kinstrie R, Horne GA, Morrison H, Irvine D, Munje C, Castañeda EG, Moka HA, Dunn K, Cassels JE, Parry N, Clarke CJ, Scott MT, Clark RE, Holyoake TL, Wheadon H, Copland M. Kinstrie R, et al. Leukemia. 2020 Jun;34(6):1613-1625. doi: 10.1038/s41375-019-0684-5. Epub 2020 Jan 2. Leukemia. 2020. PMID: 31896780 Free PMC article.
Restricted access to second generation tyrosine kinase inhibitors in the UK could result in suboptimal treatment for almost half of chronic myeloid leukaemia patients: results from a West of Scotland and Lothian population study.
Gallipoli P, Shepherd P, Irvine D, Drummond M, Holyoake T. Gallipoli P, et al. Br J Haematol. 2011 Oct;155(1):128-30. doi: 10.1111/j.1365-2141.2011.08653.x. Epub 2011 Apr 22. Br J Haematol. 2011. PMID: 21517814 Free article. No abstract available.
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile.
Cramer-Morales K, Nieborowska-Skorska M, Scheibner K, Padget M, Irvine DA, Sliwinski T, Haas K, Lee J, Geng H, Roy D, Slupianek A, Rassool FV, Wasik MA, Childers W, Copland M, Müschen M, Civin CI, Skorski T. Cramer-Morales K, et al. Blood. 2013 Aug 15;122(7):1293-304. doi: 10.1182/blood-2013-05-501072. Epub 2013 Jul 8. Blood. 2013. PMID: 23836560 Free PMC article.