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2018 6
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2024 1

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Metabolic barriers to cancer immunotherapy.
DePeaux K, Delgoffe GM. DePeaux K, et al. Nat Rev Immunol. 2021 Dec;21(12):785-797. doi: 10.1038/s41577-021-00541-y. Epub 2021 Apr 29. Nat Rev Immunol. 2021. PMID: 33927375 Free PMC article. Review.
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.
Watson MJ, Vignali PDA, Mullett SJ, Overacre-Delgoffe AE, Peralta RM, Grebinoski S, Menk AV, Rittenhouse NL, DePeaux K, Whetstone RD, Vignali DAA, Hand TW, Poholek AC, Morrison BM, Rothstein JD, Wendell SG, Delgoffe GM. Watson MJ, et al. Nature. 2021 Mar;591(7851):645-651. doi: 10.1038/s41586-020-03045-2. Epub 2021 Feb 15. Nature. 2021. PMID: 33589820 Free PMC article.
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours.
Zappasodi R, Serganova I, Cohen IJ, Maeda M, Shindo M, Senbabaoglu Y, Watson MJ, Leftin A, Maniyar R, Verma S, Lubin M, Ko M, Mane MM, Zhong H, Liu C, Ghosh A, Abu-Akeel M, Ackerstaff E, Koutcher JA, Ho PC, Delgoffe GM, Blasberg R, Wolchok JD, Merghoub T. Zappasodi R, et al. Nature. 2021 Mar;591(7851):652-658. doi: 10.1038/s41586-021-03326-4. Epub 2021 Feb 15. Nature. 2021. PMID: 33588426 Free PMC article.
Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Hahn AW, Menk AV, Rivadeneira DB, Augustin RC, Xu M, Li J, Wu X, Mishra AK, Gide TN, Quek C, Zang Y, Spencer CN, Menzies AM, Daniel CR, Hudgens CW, Nowicki T, Haydu LE, Khan MAW, Gopalakrishnan V, Burton EM, Malke J, Simon JM, Bernatchez C, Putluri N, Woodman SE, Vashisht Gopal YN, Guerrieri R, Fischer GM, Wang J, Wani KM, Thompson JF, Lee JE, Hwu P, Ajami N, Gershenwald JE, Long GV, Scolyer RA, Tetzlaff MT, Lazar AJ, Schadendorf D, Wargo JA, Kirkwood JM, DeBerardinis RJ, Liang H, Futreal A, Zhang J, Wilmott JS, Peng W, Davies MA, Delgoffe GM, Najjar YG, McQuade JL. Hahn AW, et al. Clin Cancer Res. 2023 Jan 4;29(1):154-164. doi: 10.1158/1078-0432.CCR-22-2661. Clin Cancer Res. 2023. PMID: 36166093 Free PMC article.
29 results