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Filoviral immune evasion mechanisms.
Ramanan P, Shabman RS, Brown CS, Amarasinghe GK, Basler CF, Leung DW. Ramanan P, et al. Viruses. 2011 Sep;3(9):1634-49. doi: 10.3390/v3091634. Epub 2011 Sep 7. Viruses. 2011. PMID: 21994800 Free PMC article. Review.
Ebolavirus VP35 is a multifunctional virulence factor.
Leung DW, Prins KC, Basler CF, Amarasinghe GK. Leung DW, et al. Virulence. 2010 Nov-Dec;1(6):526-31. doi: 10.4161/viru.1.6.12984. Epub 2010 Nov 1. Virulence. 2010. PMID: 21178490 Free PMC article.
Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins.
Leung DW, Borek D, Farahbakhsh M, Ramanan P, Nix JC, Wang T, Prins KC, Otwinowski Z, Honzatko RB, Helgeson LA, Basler CF, Amarasinghe GK. Leung DW, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jun 1;66(Pt 6):689-92. doi: 10.1107/S1744309110013266. Epub 2010 May 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20516601 Free PMC article.
Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.
Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK. Ramanan P, et al. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20661-6. doi: 10.1073/pnas.1213559109. Epub 2012 Nov 26. Proc Natl Acad Sci U S A. 2012. PMID: 23185024 Free PMC article.
Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Leung DW, Prins KC, Borek DM, Farahbakhsh M, Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski Z, Honzatko RB, Basler CF, Amarasinghe GK. Leung DW, et al. Nat Struct Mol Biol. 2010 Feb;17(2):165-72. doi: 10.1038/nsmb.1765. Epub 2010 Jan 17. Nat Struct Mol Biol. 2010. PMID: 20081868 Free PMC article.