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Chromatin as a key consumer in the metabolite economy.
Diehl KL, Muir TW. Diehl KL, et al. Nat Chem Biol. 2020 Jun;16(6):620-629. doi: 10.1038/s41589-020-0517-x. Epub 2020 May 22. Nat Chem Biol. 2020. PMID: 32444835 Free PMC article. Review.
PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.
Diehl KL, Ge EJ, Weinberg DN, Jani KS, Allis CD, Muir TW. Diehl KL, et al. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22152-22157. doi: 10.1073/pnas.1911775116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611394 Free PMC article.