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Equivocal, explicit and emergent actions of PKC isoforms in cancer.
Parker PJ, Brown SJ, Calleja V, Chakravarty P, Cobbaut M, Linch M, Marshall JJT, Martini S, McDonald NQ, Soliman T, Watson L. Parker PJ, et al. Nat Rev Cancer. 2021 Jan;21(1):51-63. doi: 10.1038/s41568-020-00310-4. Epub 2020 Nov 11. Nat Rev Cancer. 2021. PMID: 33177705 Review.
A cancer-associated, genome protective programme engaging PKCε.
Parker PJ, Lockwood N, Davis K, Kelly JR, Soliman TN, Pardo AL, Marshall JJT, Redmond JM, Vitale M, Silvia Martini. Parker PJ, et al. Adv Biol Regul. 2020 Dec;78:100759. doi: 10.1016/j.jbior.2020.100759. Epub 2020 Oct 7. Adv Biol Regul. 2020. PMID: 33039823 Free PMC article. Review.
Chemical Genetic Identification of PKC Epsilon Substrates in Mouse Brain.
Dugan MP, Ferguson LB, Hertz NT, Chalkley RJ, Burlingame AL, Shokat KM, Parker PJ, Messing RO. Dugan MP, et al. Mol Cell Proteomics. 2023 Apr;22(4):100522. doi: 10.1016/j.mcpro.2023.100522. Epub 2023 Feb 28. Mol Cell Proteomics. 2023. PMID: 36863607 Free PMC article.
High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment.
Sánchez-Magraner L, Miles J, Baker CL, Applebee CJ, Lee DJ, Elsheikh S, Lashin S, Withers K, Watts AG, Parry R, Edmead C, Lopez JI, Mehta R, Italiano A, Ward SG, Parker PJ, Larijani B. Sánchez-Magraner L, et al. Cancer Res. 2020 Oct 1;80(19):4244-4257. doi: 10.1158/0008-5472.CAN-20-1117. Epub 2020 Aug 27. Cancer Res. 2020. PMID: 32855204
A small molecule inhibitor of HER3: a proof-of-concept study.
Colomba A, Fitzek M, George R, Weitsman G, Roberts S, Zanetti-Domingues L, Hirsch M, Rolfe DJ, Mehmood S, Madin A, Claus J, Kjaer S, Snijders AP, Ng T, Martin-Fernandez M, Smith DM, Parker PJ. Colomba A, et al. Biochem J. 2020 Sep 18;477(17):3329-3347. doi: 10.1042/BCJ20200496. Biochem J. 2020. PMID: 32815546 Free PMC article.
14 results