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29 results

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Page 1
Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study).
Mothe B, Manzardo C, Sanchez-Bernabeu A, Coll P, Morón-López S, Puertas MC, Rosas-Umbert M, Cobarsi P, Escrig R, Perez-Alvarez N, Ruiz I, Rovira C, Meulbroek M, Crook A, Borthwick N, Wee EG, Yang H, Miró JM, Dorrell L, Clotet B, Martinez-Picado J, Brander C, Hanke T. Mothe B, et al. EClinicalMedicine. 2019 Jun 5;11:65-80. doi: 10.1016/j.eclinm.2019.05.009. eCollection 2019 May-Jun. EClinicalMedicine. 2019. PMID: 31312806 Free PMC article.
Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.
Borthwick N, Ahmed T, Ondondo B, Hayes P, Rose A, Ebrahimsa U, Hayton EJ, Black A, Bridgeman A, Rosario M, Hill AV, Berrie E, Moyle S, Frahm N, Cox J, Colloca S, Nicosia A, Gilmour J, McMichael AJ, Dorrell L, Hanke T. Borthwick N, et al. Mol Ther. 2014 Feb;22(2):464-475. doi: 10.1038/mt.2013.248. Epub 2013 Oct 31. Mol Ther. 2014. PMID: 24166483 Free PMC article.
Preserved central nervous system functioning after use of romidepsin as a latency-reversing agent in an HIV cure strategy.
Muñoz-Moreno JA, Carrillo-Molina S, Martínez-Zalacaín I, Miranda C, Manzardo C, Coll P, Meulbroek M, Hanke T, Garolera M, Miró JM, Brander C, Clotet B, Soriano-Mas C, Moltó J, Mothe B; BCN02-Neuro Substudy Group. Muñoz-Moreno JA, et al. AIDS. 2022 Mar 1;36(3):363-372. doi: 10.1097/QAD.0000000000003121. AIDS. 2022. PMID: 34750296 Clinical Trial.
No evidence of neuronal damage as measured by neurofilament light chain in a HIV cure study utilising a kick-and-kill approach.
Alagaratnam J, Stöhr W, Toombs J, Heslegrave A, Zetterberg H, Gisslén M, Pett S, Nelson M, Clarke A, Nwokolo N, Johnson MA, Khan M, Hanke T, Kopycinski J, Dorrell L, Fox J, Kinloch S, Underwood J, Pace M, Frater J, Winston A, Fidler S; RIVER trial study group. Alagaratnam J, et al. J Virus Erad. 2021 Sep 14;7(3):100056. doi: 10.1016/j.jve.2021.100056. eCollection 2021 Sep. J Virus Erad. 2021. PMID: 34611495 Free PMC article.
Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults.
Mutua G, Farah B, Langat R, Indangasi J, Ogola S, Onsembe B, Kopycinski JT, Hayes P, Borthwick NJ, Ashraf A, Dally L, Barin B, Tillander A, Gilmour J, De Bont J, Crook A, Hannaman D, Cox JH, Anzala O, Fast PE, Reilly M, Chinyenze K, Jaoko W, Hanke T, Hiv-Core 004 Study Group T. Mutua G, et al. Mol Ther Methods Clin Dev. 2016 Aug 31;3:16061. doi: 10.1038/mtm.2016.61. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27617268 Free PMC article.
29 results