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SNARE protein SEC22B regulates early embryonic development.
Wu SJ, Khoriaty R, Kim SH, O'Shea KS, Zhu G, Hoenerhoff M, Zajac C, Oravecz-Wilson K, Toubai T, Sun Y, Ginsburg D, Reddy P. Wu SJ, et al. Sci Rep. 2019 Aug 7;9(1):11434. doi: 10.1038/s41598-019-46536-7. Sci Rep. 2019. PMID: 31391476 Free PMC article.
Murine Surf4 is essential for early embryonic development.
Emmer BT, Lascuna PJ, Tang VT, Kotnik EN, Saunders TL, Khoriaty R, Ginsburg D. Emmer BT, et al. PLoS One. 2020 Jan 24;15(1):e0227450. doi: 10.1371/journal.pone.0227450. eCollection 2020. PLoS One. 2020. PMID: 31978056 Free PMC article.
The COPII cargo adapter SEC24C is essential for neuronal homeostasis.
Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M. Wang B, et al. J Clin Invest. 2018 Aug 1;128(8):3319-3332. doi: 10.1172/JCI98194. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29939162 Free PMC article.
Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.
Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D. Khoriaty R, et al. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7748-E7757. doi: 10.1073/pnas.1805784115. Epub 2018 Jul 31. Proc Natl Acad Sci U S A. 2018. PMID: 30065114 Free PMC article.
SEC23B is required for pancreatic acinar cell function in adult mice.
Khoriaty R, Vogel N, Hoenerhoff MJ, Sans MD, Zhu G, Everett L, Nelson B, Durairaj H, McKnight B, Zhang B, Ernst SA, Ginsburg D, Williams JA. Khoriaty R, et al. Mol Biol Cell. 2017 Jul 15;28(15):2146-2154. doi: 10.1091/mbc.E17-01-0001. Epub 2017 May 24. Mol Biol Cell. 2017. PMID: 28539403 Free PMC article.
11 results