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Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders.
Saffouri GB, Shields-Cutler RR, Chen J, Yang Y, Lekatz HR, Hale VL, Cho JM, Battaglioli EJ, Bhattarai Y, Thompson KJ, Kalari KK, Behera G, Berry JC, Peters SA, Patel R, Schuetz AN, Faith JJ, Camilleri M, Sonnenburg JL, Farrugia G, Swann JR, Grover M, Knights D, Kashyap PC. Saffouri GB, et al. Nat Commun. 2019 May 1;10(1):2012. doi: 10.1038/s41467-019-09964-7. Nat Commun. 2019. PMID: 31043597 Free PMC article. Clinical Trial.
Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion.
Bhattarai Y, Williams BB, Battaglioli EJ, Whitaker WR, Till L, Grover M, Linden DR, Akiba Y, Kandimalla KK, Zachos NC, Kaunitz JD, Sonnenburg JL, Fischbach MA, Farrugia G, Kashyap PC. Bhattarai Y, et al. Cell Host Microbe. 2018 Jun 13;23(6):775-785.e5. doi: 10.1016/j.chom.2018.05.004. Cell Host Microbe. 2018. PMID: 29902441 Free PMC article.
Post-infection Irritable Bowel Syndrome.
Berumen A, Edwinson AL, Grover M. Berumen A, et al. Gastroenterol Clin North Am. 2021 Jun;50(2):445-461. doi: 10.1016/j.gtc.2021.02.007. Epub 2021 Apr 23. Gastroenterol Clin North Am. 2021. PMID: 34024451 Free PMC article. Review.
Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome.
Edwinson AL, Yang L, Peters S, Hanning N, Jeraldo P, Jagtap P, Simpson JB, Yang TY, Kumar P, Mehta S, Nair A, Breen-Lyles M, Chikkamenahalli L, Graham RP, De Winter B, Patel R, Dasari S, Kashyap P, Griffin T, Chen J, Farrugia G, Redinbo MR, Grover M. Edwinson AL, et al. Nat Microbiol. 2022 May;7(5):680-694. doi: 10.1038/s41564-022-01103-1. Epub 2022 Apr 28. Nat Microbiol. 2022. PMID: 35484230 Free PMC article.
Duodenal mucosal secretory disturbances in functional dyspepsia.
Puthanmadhom Narayanan S, Linden DR, Peters SA, Desai A, Kuwelker S, O'Brien D, Smyrk TJ, Graham RP, Grover M, Bharucha AE. Puthanmadhom Narayanan S, et al. Neurogastroenterol Motil. 2021 Jan;33(1):e13955. doi: 10.1111/nmo.13955. Epub 2020 Aug 9. Neurogastroenterol Motil. 2021. PMID: 32776463 Free PMC article.
Expert consensus document: Advances in the diagnosis and classification of gastric and intestinal motility disorders.
Keller J, Bassotti G, Clarke J, Dinning P, Fox M, Grover M, Hellström PM, Ke M, Layer P, Malagelada C, Parkman HP, Scott SM, Tack J, Simren M, Törnblom H, Camilleri M; International Working Group for Disorders of Gastrointestinal Motility and Function. Keller J, et al. Nat Rev Gastroenterol Hepatol. 2018 May;15(5):291-308. doi: 10.1038/nrgastro.2018.7. Epub 2018 Apr 6. Nat Rev Gastroenterol Hepatol. 2018. PMID: 29622808 Free PMC article. Review.
32 results