Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes.
Hivert MF, White F, Allard C, James K, Majid S, Aguet F, Ardlie KG, Florez JC, Edlow AG, Bouchard L, Jacques PÉ, Karumanchi SA, Powe CE.
Hivert MF, et al.
Nat Med. 2024 Jun;30(6):1689-1695. doi: 10.1038/s41591-024-02936-5. Epub 2024 Apr 16.
Nat Med. 2024.
PMID: 38627562
Free PMC article.
We conducted transcriptomic profiling of 434 human placentas and identified a positive association between insulin-like growth factor binding protein 1 gene (IGFBP1) expression in the placenta and insulin sensitivity at ~26 weeks gestation. ...
We conducted transcriptomic profiling of 434 human placentas and identified a positive association between insulin-like growth factor …