K99 NS120278/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	2
2022	1
2023	4
2024	1

1

Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength.

Palla AR, Ravichandran M, Wang YX, Alexandrova L, Yang AV, Kraft P, Holbrook CA, Schürch CM, Ho ATV, Blau HM. Palla AR, et al. Science. 2021 Jan 29;371(6528):eabc8059. doi: 10.1126/science.abc8059. Epub 2020 Dec 10. Science. 2021. PMID: 33303683 Free PMC article.

2

Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.

Zengel J, Wang YX, Seo JW, Ning K, Hamilton JN, Wu B, Raie M, Holbrook C, Su S, Clements DR, Pillay S, Puschnik AS, Winslow MM, Idoyaga J, Nagamine CM, Sun Y, Mahajan VB, Ferrara KW, Blau HM, Carette JE. Zengel J, et al. Nat Methods. 2023 Jul;20(7):1070-1081. doi: 10.1038/s41592-023-01896-x. Epub 2023 Jun 8. Nat Methods. 2023. PMID: 37291262 Free PMC article.

3

Regeneration of neuromuscular synapses after acute and chronic denervation by inhibiting the gerozyme 15-prostaglandin dehydrogenase.

Bakooshli MA, Wang YX, Monti E, Su S, Kraft P, Nalbandian M, Alexandrova L, Wheeler JR, Vogel H, Blau HM. Bakooshli MA, et al. Sci Transl Med. 2023 Oct 11;15(717):eadg1485. doi: 10.1126/scitranslmed.adg1485. Epub 2023 Oct 11. Sci Transl Med. 2023. PMID: 37820010 Free PMC article.

4

Sex biased human thymic architecture guides T cell development through spatially defined niches.

Stankiewicz LN, Salim K, Flaschner EA, Wang YX, Edgar JM, Lin BZ, Bingham GC, Major MC, Jones RD, Blau HM, Rideout EJ, Levings MK, Zandstra PW, Rossi FM. Stankiewicz LN, et al. bioRxiv [Preprint]. 2023 Apr 16:2023.04.13.536804. doi: 10.1101/2023.04.13.536804. bioRxiv. 2023. Update in: Dev Cell. 2024 Oct 3:S1534-5807(24)00539-2. doi: 10.1016/j.devcel.2024.09.011. PMID: 37090676 Free PMC article. Updated. Preprint.

5

Hydrogel biomaterials that stiffen and soften on demand reveal that skeletal muscle stem cells harbor a mechanical memory.

Madl CM, Wang YX, Holbrook CA, Su S, Shi X, Byfield FJ, Wicki G, Flaig IA, Blau HM. Madl CM, et al. Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2406787121. doi: 10.1073/pnas.2406787121. Epub 2024 Aug 20. Proc Natl Acad Sci U S A. 2024. PMID: 39163337

6

Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments.

Madl CM, Flaig IA, Holbrook CA, Wang YX, Blau HM. Madl CM, et al. Biomaterials. 2021 Aug;275:120973. doi: 10.1016/j.biomaterials.2021.120973. Epub 2021 Jun 14. Biomaterials. 2021. PMID: 34224984 Free PMC article.

7

Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors.

Togninalli M, Ho ATV, Madl CM, Holbrook CA, Wang YX, Magnusson KEG, Kirillova A, Chang A, Blau HM. Togninalli M, et al. NPJ Regen Med. 2023 Jan 14;8(1):4. doi: 10.1038/s41536-023-00277-4. NPJ Regen Med. 2023. PMID: 36639373 Free PMC article.

8

Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging.

Palla AR, Hilgendorf KI, Yang AV, Kerr JP, Hinken AC, Demeter J, Kraft P, Mooney NA, Yucel N, Burns DM, Wang YX, Jackson PK, Blau HM. Palla AR, et al. Nat Commun. 2022 Mar 17;13(1):1439. doi: 10.1038/s41467-022-29150-6. Nat Commun. 2022. PMID: 35301320 Free PMC article.

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