MR/V028391/1/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	8
2022	7
2023	3
2024	0

1

Prescribing Nirmatrelvir-Ritonavir: How to Recognize and Manage Drug-Drug Interactions.

Marzolini C, Kuritzkes DR, Marra F, Boyle A, Gibbons S, Flexner C, Pozniak A, Boffito M, Waters L, Burger D, Back D, Khoo S. Marzolini C, et al. Ann Intern Med. 2022 May;175(5):744-746. doi: 10.7326/M22-0281. Epub 2022 Mar 1. Ann Intern Med. 2022. PMID: 35226530 Free PMC article.

2

Fluvoxamine for the treatment of COVID-19.

Marzolini C, Marra F, Boyle A, Khoo S, Back DJ. Marzolini C, et al. Lancet Glob Health. 2022 Mar;10(3):e331. doi: 10.1016/S2214-109X(21)00592-1. Lancet Glob Health. 2022. PMID: 35180411 Free PMC article. No abstract available.

3

The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva.

Amara A, Penchala SD, Else L, Hale C, FitzGerald R, Walker L, Lyons R, Fletcher T, Khoo S. Amara A, et al. J Pharm Biomed Anal. 2021 Nov 30;206:114356. doi: 10.1016/j.jpba.2021.114356. Epub 2021 Sep 2. J Pharm Biomed Anal. 2021. PMID: 34509661 Free PMC article.

4

Shutting the gate before the horse has bolted: is it time for a conversation about SARS-CoV-2 and antiviral drug resistance?

Hiscox JA, Khoo SH, Stewart JP, Owen A. Hiscox JA, et al. J Antimicrob Chemother. 2021 Aug 12;76(9):2230-2233. doi: 10.1093/jac/dkab189. J Antimicrob Chemother. 2021. PMID: 34142123 Free PMC article. Review.

5

Development and validation of an LC-MS/MS method for quantification of favipiravir in human plasma.

Challenger E, Penchala SD, Hale C, Fitzgerald R, Walker L, Reynolds H, Chiong J, Fletcher T, Khoo S, Else L. Challenger E, et al. J Pharm Biomed Anal. 2023 Sep 5;233:115436. doi: 10.1016/j.jpba.2023.115436. Epub 2023 May 2. J Pharm Biomed Anal. 2023. PMID: 37148698 Free article.

6

Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.

Rajoli RKR, Pertinez H, Arshad U, Box H, Tatham L, Curley P, Neary M, Sharp J, Liptrott NJ, Valentijn A, David C, Rannard SP, Aljayyoussi G, Pennington SH, Hill A, Boffito M, Ward SA, Khoo SH, Bray PG, O'Neill PM, Hong WD, Biagini GA, Owen A. Rajoli RKR, et al. Br J Clin Pharmacol. 2021 Apr;87(4):2078-2088. doi: 10.1111/bcp.14619. Epub 2020 Dec 1. Br J Clin Pharmacol. 2021. PMID: 33085781 Free PMC article.

7

Practical recommendations for implementing a Bayesian adaptive phase I design during a pandemic.

Ewings S, Saunders G, Jaki T, Mozgunov P. Ewings S, et al. BMC Med Res Methodol. 2022 Jan 20;22(1):25. doi: 10.1186/s12874-022-01512-0. BMC Med Res Methodol. 2022. PMID: 35057758 Free PMC article.

8

Application of novel plasma separation filter cards for quantification of nucleoside/nucleotide reverse transcriptase inhibitor di/triphosphates in dried blood spots using LC-MS.

Thompson B, Dilly-Penchala S, Amara A, Reynolds H, Khoo S, Else L. Thompson B, et al. Bioanalysis. 2023 Jul;15(13):739-756. doi: 10.4155/bio-2023-0057. Epub 2023 Jun 9. Bioanalysis. 2023. PMID: 37293769 Free PMC article.

9

Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2.

Pertinez H, Rajoli RK, Khoo SH, Owen A. Pertinez H, et al. medRxiv [Preprint]. 2021 Jan 5:2021.01.03.21249159. doi: 10.1101/2021.01.03.21249159. medRxiv. 2021. Update in: J Antimicrob Chemother. 2021 Jul 15;76(8):2121-2128. doi: 10.1093/jac/dkab135. PMID: 33442711 Free PMC article. Updated. Preprint.

10

Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2.

Pertinez H, Rajoli RKR, Khoo SH, Owen A. Pertinez H, et al. J Antimicrob Chemother. 2021 Jul 15;76(8):2121-2128. doi: 10.1093/jac/dkab135. J Antimicrob Chemother. 2021. PMID: 34075418 Free PMC article.

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