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Histone deacetylase function in CD4+ T cells.
Ellmeier W, Seiser C. Ellmeier W, et al. Nat Rev Immunol. 2018 Oct;18(10):617-634. doi: 10.1038/s41577-018-0037-z. Nat Rev Immunol. 2018. PMID: 30022149 Review.
Vorinostat in the acute neuroinflammatory form of X-linked adrenoleukodystrophy.
Zierfuss B, Weinhofer I, Kühl JS, Köhler W, Bley A, Zauner K, Binder J, Martinović K, Seiser C, Hertzberg C, Kemp S, Egger G, Leitner G, Bauer J, Wiesinger C, Kunze M, Forss-Petter S, Berger J. Zierfuss B, et al. Ann Clin Transl Neurol. 2020 May;7(5):639-652. doi: 10.1002/acn3.51015. Epub 2020 May 2. Ann Clin Transl Neurol. 2020. PMID: 32359032 Free PMC article.
Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation.
Preglej T, Hamminger P, Luu M, Bulat T, Andersen L, Göschl L, Stolz V, Rica R, Sandner L, Waltenberger D, Tschismarov R, Faux T, Boenke T, Laiho A, Elo LL, Sakaguchi S, Steiner G, Decker T, Bohle B, Visekruna A, Bock C, Strobl B, Seiser C, Boucheron N, Ellmeier W. Preglej T, et al. JCI Insight. 2020 Feb 27;5(4):e133393. doi: 10.1172/jci.insight.133393. JCI Insight. 2020. PMID: 32102981 Free PMC article.
Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis.
Göschl L, Preglej T, Boucheron N, Saferding V, Müller L, Platzer A, Hirahara K, Shih HY, Backlund J, Matthias P, Niederreiter B, Hladik A, Kugler M, Gualdoni GA, Scheinecker C, Knapp S, Seiser C, Holmdahl R, Tillmann K, Plasenzotti R, Podesser B, Aletaha D, Smolen JS, Karonitsch T, Steiner G, Ellmeier W, Bonelli M. Göschl L, et al. J Autoimmun. 2020 Mar;108:102379. doi: 10.1016/j.jaut.2019.102379. Epub 2019 Dec 26. J Autoimmun. 2020. PMID: 31883829
A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.
Göschl L, Preglej T, Hamminger P, Bonelli M, Andersen L, Boucheron N, Gülich AF, Müller L, Saferding V, Mufazalov IA, Hirahara K, Seiser C, Matthias P, Penz T, Schuster M, Bock C, Waisman A, Steiner G, Ellmeier W. Göschl L, et al. J Autoimmun. 2018 Jan;86:51-61. doi: 10.1016/j.jaut.2017.09.008. Epub 2017 Sep 28. J Autoimmun. 2018. PMID: 28964722