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A phase I study of bortezomib and temozolomide in patients with advanced solid tumors.
Portnow J, Frankel P, Koehler S, Twardowski P, Shibata S, Martel C, Morgan R, Cristea M, Chow W, Lim D, Chung V, Reckamp K, Leong L, Synold TW. Portnow J, et al. Cancer Chemother Pharmacol. 2012 Feb;69(2):505-14. doi: 10.1007/s00280-011-1721-x. Epub 2011 Aug 18. Cancer Chemother Pharmacol. 2012. PMID: 21850464 Free PMC article. Clinical Trial.
A phase I/II prospective, single arm trial of gefitinib, trastuzumab, and docetaxel in patients with stage IV HER-2 positive metastatic breast cancer.
Somlo G, Martel CL, Lau SK, Frankel P, Ruel C, Gu L, Hurria A, Chung C, Luu T, Morgan R Jr, Leong L, Koczywas M, McNamara M, Russell CA, Kane SE. Somlo G, et al. Breast Cancer Res Treat. 2012 Feb;131(3):899-906. doi: 10.1007/s10549-011-1850-2. Epub 2011 Nov 1. Breast Cancer Res Treat. 2012. PMID: 22042372 Free PMC article. Clinical Trial.
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development.
Buettner R, Corzano R, Rashid R, Lin J, Senthil M, Hedvat M, Schroeder A, Mao A, Herrmann A, Yim J, Li H, Yuan YC, Yakushijin K, Yakushijin F, Vaidehi N, Moore R, Gugiu G, Lee TD, Yip R, Chen Y, Jove R, Horne D, Williams JC. Buettner R, et al. ACS Chem Biol. 2011 May 20;6(5):432-43. doi: 10.1021/cb100253e. Epub 2011 Feb 16. ACS Chem Biol. 2011. PMID: 21226522 Free PMC article.
13 results