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Deletional tolerance mediated by extrathymic Aire-expressing cells.
Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Gardner JM, et al. Science. 2008 Aug 8;321(5890):843-7. doi: 10.1126/science.1159407. Science. 2008. PMID: 18687966 Free PMC article.
Serotonin regulates pancreatic beta cell mass during pregnancy.
Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, Mizukami H, Fujitani Y, Kawamori R, Miyatsuka T, Kosaka Y, Yang K, Honig G, van der Hart M, Kishimoto N, Wang J, Yagihashi S, Tecott LH, Watada H, German MS. Kim H, et al. Nat Med. 2010 Jul;16(7):804-8. doi: 10.1038/nm.2173. Epub 2010 Jun 27. Nat Med. 2010. PMID: 20581837 Free PMC article.
Rfx6 directs islet formation and insulin production in mice and humans.
Smith SB, Qu HQ, Taleb N, Kishimoto NY, Scheel DW, Lu Y, Patch AM, Grabs R, Wang J, Lynn FC, Miyatsuka T, Mitchell J, Seerke R, Désir J, Vanden Eijnden S, Abramowicz M, Kacet N, Weill J, Renard ME, Gentile M, Hansen I, Dewar K, Hattersley AT, Wang R, Wilson ME, Johnson JD, Polychronakos C, German MS. Smith SB, et al. Nature. 2010 Feb 11;463(7282):775-80. doi: 10.1038/nature08748. Nature. 2010. PMID: 20148032 Free PMC article.
Dachshund homologues play a conserved role in islet cell development.
Kalousova A, Mavropoulos A, Adams BA, Nekrep N, Li Z, Krauss S, Stainier DY, German MS. Kalousova A, et al. Dev Biol. 2010 Dec 15;348(2):143-52. doi: 10.1016/j.ydbio.2010.09.007. Epub 2010 Sep 30. Dev Biol. 2010. PMID: 20869363 Free PMC article.