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Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.
Aging (Albany NY). 2013 Dec;5(12):867-83. doi: 10.18632/aging.100621.
Aging (Albany NY). 2013.
PMID: 24323947
Free PMC article.
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements.
De Cecco M, Criscione SW, Peckham EJ, Hillenmeyer S, Hamm EA, Manivannan J, Peterson AL, Kreiling JA, Neretti N, Sedivy JM.
De Cecco M, et al.
Aging Cell. 2013 Apr;12(2):247-56. doi: 10.1111/acel.12047. Epub 2013 Jan 30.
Aging Cell. 2013.
PMID: 23360310
Free PMC article.
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