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Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.
Simhadri S, Peterson S, Patel DS, Huo Y, Cai H, Bowman-Colin C, Miller S, Ludwig T, Ganesan S, Bhaumik M, Bunting SF, Jasin M, Xia B. Simhadri S, et al. J Biol Chem. 2014 Aug 29;289(35):24617-29. doi: 10.1074/jbc.M114.566141. Epub 2014 Jul 11. J Biol Chem. 2014. PMID: 25016020 Free PMC article.
Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Bowman-Colin C, Xia B, Bunting S, Klijn C, Drost R, Bouwman P, Fineman L, Chen X, Culhane AC, Cai H, Rodig SJ, Bronson RT, Jonkers J, Nussenzweig A, Kanellopoulou C, Livingston DM. Bowman-Colin C, et al. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8632-7. doi: 10.1073/pnas.1305362110. Epub 2013 May 8. Proc Natl Acad Sci U S A. 2013. PMID: 23657012 Free PMC article.
53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.
Li M, Cole F, Patel DS, Misenko SM, Her J, Malhowski A, Alhamza A, Zheng H, Baer R, Ludwig T, Jasin M, Nussenzweig A, Serrano L, Bunting SF. Li M, et al. EMBO Rep. 2016 Nov;17(11):1532-1541. doi: 10.15252/embr.201642497. Epub 2016 Sep 26. EMBO Rep. 2016. PMID: 27670884 Free PMC article.