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Brain cell type-specific enhancer-promoter interactome maps and disease-risk association.
Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. Nott A, et al. Science. 2019 Nov 29;366(6469):1134-1139. doi: 10.1126/science.aay0793. Epub 2019 Nov 14. Science. 2019. PMID: 31727856 Free PMC article.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Thomas DD, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. EMBO J. 2022 Nov 2;41(21):e110393. doi: 10.15252/embj.2021110393. Epub 2022 Oct 10. EMBO J. 2022. PMID: 36215696 Free PMC article.
Genetic signature of human longevity in PKC and NF-κB signaling.
Ryu S, Han J, Norden-Krichmar TM, Zhang Q, Lee S, Zhang Z, Atzmon G, Niedernhofer LJ, Robbins PD, Barzilai N, Schork NJ, Suh Y. Ryu S, et al. Aging Cell. 2021 Jul;20(7):e13362. doi: 10.1111/acel.13362. Epub 2021 Jul 1. Aging Cell. 2021. PMID: 34197020 Free PMC article.
Polygenic prediction of human longevity on the supposition of pervasive pleiotropy.
Jabalameli MR, Lin JR, Zhang Q, Wang Z, Mitra J, Nguyen N, Gao T, Khusidman M, Atzmon G, Milman S, Vijg J, Barzilai N, Zhang ZD. Jabalameli MR, et al. medRxiv [Preprint]. 2023 Dec 11:2023.12.10.23299795. doi: 10.1101/2023.12.10.23299795. medRxiv. 2023. Update in: Sci Rep. 2024 Aug 28;14(1):19981. doi: 10.1038/s41598-024-69069-0. PMID: 38168353 Free PMC article. Updated. Preprint.