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Page 1
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.
Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D. Piehl N, et al. Cell. 2022 Dec 22;185(26):5028-5039.e13. doi: 10.1016/j.cell.2022.11.019. Epub 2022 Dec 13. Cell. 2022. PMID: 36516855 Free PMC article.
The pathotome and precision health.
Younes K, Mormino EC. Younes K, et al. Brain. 2023 Jun 1;146(6):2208-2210. doi: 10.1093/brain/awad154. Brain. 2023. PMID: 37150902 Free PMC article.
Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes.
Abiose O, Rutledge J, Moran-Losada P, Belloy ME, Wilson EN, He Z, Trelle AN, Channappa D, Romero A, Park J, Yutsis MV, Sha SJ, Andreasson KI, Poston KL, Henderson VW, Wagner AD, Wyss-Coray T, Mormino EC. Abiose O, et al. Alzheimers Dement. 2024 Mar;20(3):1851-1867. doi: 10.1002/alz.13576. Epub 2023 Dec 25. Alzheimers Dement. 2024. PMID: 38146099 Free PMC article.
A 3'UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP.
Chemparathy A, Guen YL, Zeng Y, Gorzynski J, Jensen T, Yang C, Kasireddy N, Talozzi L, Belloy ME, Stewart I, Gitler AD, Wagner AD, Mormino E, Henderson VW, Wyss-Coray T, Ashley E, Cruchaga C, Greicius MD. Chemparathy A, et al. medRxiv [Preprint]. 2023 Nov 17:2023.07.06.23292312. doi: 10.1101/2023.07.06.23292312. medRxiv. 2023. PMID: 37461476 Free PMC article. Preprint.
Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction.
Wilson E, Umans J, Swarovski M, Minhas P, Midttun Ø, Ulvik AA, Shahid-Besanti M, Linortner P, Mhatre S, Wang Q, Channappa D, Corso N, Tian L, Fredericks C, Kerchner G, Plowey E, Cholerton B, Ueland P, Zabetian C, Gray N, Quinn J, Montine T, Sha S, Longo F, Wolk D, Chen-Plotkin A, Henderson V, Wyss-Coray T, Wagner A, Mormino E, Aghaeepour N, Poston K, Andreasson K. Wilson E, et al. Res Sq [Preprint]. 2024 Sep 26:rs.3.rs-4980210. doi: 10.21203/rs.3.rs-4980210/v1. Res Sq. 2024. PMID: 39399688 Free PMC article. Preprint.
Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.
Jensen TD, Ni B, Reuter CM, Gorzynski JE, Fazal S, Bonner D, Ungar RA, Goddard PC, Raja A, Ashley EA, Bernstein JA, Zuchner S; Undiagnosed Diseases Network; Greicius MD, Montgomery SB, Schatz MC, Wheeler MT, Battle A. Jensen TD, et al. medRxiv [Preprint]. 2024 Mar 26:2024.03.22.24304565. doi: 10.1101/2024.03.22.24304565. medRxiv. 2024. PMID: 38585781 Free PMC article. Preprint.