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Role of Senescent Cells in Cutaneous Wound Healing.
Andrade AM, Sun M, Gasek NS, Hargis GR, Sharafieh R, Xu M. Andrade AM, et al. Biology (Basel). 2022 Nov 29;11(12):1731. doi: 10.3390/biology11121731. Biology (Basel). 2022. PMID: 36552241 Free PMC article. Review.
Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function.
Wang B, Wang L, Gasek NS, Kuo CL, Nie J, Kim T, Yan P, Zhu J, Torrance BL, Zhou Y, Flores LC, Allen C, Andrade AM, Guo C, Cohn RL, Jellison ER, Bartley JM, Kuchel GA, Li S, Pirtskhalava T, Tchkonia T, Yadav S, Haynes L, Kirkland JL, Ikeno Y, Xu M. Wang B, et al. Cell Metab. 2024 Aug 6;36(8):1795-1805.e6. doi: 10.1016/j.cmet.2024.07.006. Cell Metab. 2024. PMID: 39111286
Human Rotator Cuff Tears Reveal an Age-Dependent Increase in Markers of Cellular Senescence and Selective Removal of Senescent Cells With Dasatinib + Quercetin Increases Genetic Expression of COL1A1 In Vitro.
Hawthorne BC, Wellington IJ, Sabitsky JT, Murphy KV, Karsmarski OP, Thomas RO, LeVasseur MR, Mancini MR, Trudeau MT, Gulati S, McCarthy MBR, Cote MP, Xu M, Mazzocca AD. Hawthorne BC, et al. Arthroscopy. 2024 Jan;40(1):34-44. doi: 10.1016/j.arthro.2023.05.036. Epub 2023 Jun 23. Arthroscopy. 2024. PMID: 37356505 Free PMC article.