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Lrp1 is a host entry factor for Rift Valley fever virus.
Ganaie SS, Schwarz MM, McMillen CM, Price DA, Feng AX, Albe JR, Wang W, Miersch S, Orvedahl A, Cole AR, Sentmanat MF, Mishra N, Boyles DA, Koenig ZT, Kujawa MR, Demers MA, Hoehl RM, Moyle AB, Wagner ND, Stubbs SH, Cardarelli L, Teyra J, McElroy A, Gross ML, Whelan SPJ, Doench J, Cui X, Brett TJ, Sidhu SS, Virgin HW, Egawa T, Leung DW, Amarasinghe GK, Hartman AL. Ganaie SS, et al. Cell. 2021 Sep 30;184(20):5163-5178.e24. doi: 10.1016/j.cell.2021.09.001. Epub 2021 Sep 23. Cell. 2021. PMID: 34559985 Free PMC article.
Thymic development of gut-microbiota-specific T cells.
Zegarra-Ruiz DF, Kim DV, Norwood K, Kim M, Wu WH, Saldana-Morales FB, Hill AA, Majumdar S, Orozco S, Bell R, Round JL, Longman RS, Egawa T, Bettini ML, Diehl GE. Zegarra-Ruiz DF, et al. Nature. 2021 Jun;594(7863):413-417. doi: 10.1038/s41586-021-03531-1. Epub 2021 May 12. Nature. 2021. PMID: 33981034 Free PMC article.
Divergent clonal differentiation trajectories of T cell exhaustion.
Daniel B, Yost KE, Hsiung S, Sandor K, Xia Y, Qi Y, Hiam-Galvez KJ, Black M, J Raposo C, Shi Q, Meier SL, Belk JA, Giles JR, Wherry EJ, Chang HY, Egawa T, Satpathy AT. Daniel B, et al. Nat Immunol. 2022 Nov;23(11):1614-1627. doi: 10.1038/s41590-022-01337-5. Epub 2022 Oct 26. Nat Immunol. 2022. PMID: 36289450 Free PMC article.
Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.
Liu TT, Kim S, Desai P, Kim DH, Huang X, Ferris ST, Wu R, Ou F, Egawa T, Van Dyken SJ, Diamond MS, Johnson PF, Kubo M, Murphy TL, Murphy KM. Liu TT, et al. Nature. 2022 Jul;607(7917):142-148. doi: 10.1038/s41586-022-04866-z. Epub 2022 Jun 22. Nature. 2022. PMID: 35732734 Free PMC article.
Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice.
Schwarz MM, Ganaie SS, Feng A, Brown G, Yangdon T, White JM, Hoehl RM, McMillen CM, Rush RE, Connors KA, Cui X, Leung DW, Egawa T, Amarasinghe GK, Hartman AL. Schwarz MM, et al. Sci Adv. 2023 Jul 14;9(28):eadh2264. doi: 10.1126/sciadv.adh2264. Epub 2023 Jul 14. Sci Adv. 2023. PMID: 37450601 Free PMC article.
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1.
Schwarz MM, Price DA, Ganaie SS, Feng A, Mishra N, Hoehl RM, Fatma F, Stubbs SH, Whelan SPJ, Cui X, Egawa T, Leung DW, Amarasinghe GK, Hartman AL. Schwarz MM, et al. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2204706119. doi: 10.1073/pnas.2204706119. Epub 2022 Aug 8. Proc Natl Acad Sci U S A. 2022. PMID: 35939689 Free PMC article.
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