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The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection.
Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann S, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, Aye PP, Lifson JD, Beddingfield BJ, Blair RV, Bohm RP, Kolls JK, Rappaport J, Hoxie JA, Maness NJ. Melton A, et al. bioRxiv [Preprint]. 2023 Nov 16:2023.11.15.567132. doi: 10.1101/2023.11.15.567132. bioRxiv. 2023. Update in: Viruses. 2024 Jul 21;16(7):1173. doi: 10.3390/v16071173. PMID: 38014096 Free PMC article. Updated. Preprint.
A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection.
Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, Wiseman RW, Fennessey CM, Li Y, Piatak M Jr, Lifson JD, LaBranche CC, Lackner AA, Keele BF, Maness NJ, Marsh M, Hoxie JA. Lawrence SP, et al. PLoS Pathog. 2022 Jun 17;18(6):e1010507. doi: 10.1371/journal.ppat.1010507. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35714165 Free PMC article.
The Impact of SIV-Induced Immunodeficiency on SARS-CoV-2 Disease, Viral Dynamics, and Antiviral Immune Response in a Nonhuman Primate Model of Coinfection.
Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann SE, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, Aye PP, Lifson JD, Beddingfield BJ, Blair RV, Bohm RP, Kolls JK, Rappaport J, Hoxie JA, Maness NJ. Melton A, et al. Viruses. 2024 Jul 21;16(7):1173. doi: 10.3390/v16071173. Viruses. 2024. PMID: 39066335 Free PMC article.