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Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses.
Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. Cell Rep Med. 2023 May 16;4(5):101024. doi: 10.1016/j.xcrm.2023.101024. Epub 2023 Apr 28. Cell Rep Med. 2023. PMID: 37119814 Free PMC article.
Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses.
Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524824. doi: 10.1101/2023.01.19.524824. bioRxiv. 2023. Update in: Cell Rep Med. 2023 May 16;4(5):101024. doi: 10.1016/j.xcrm.2023.101024. PMID: 36711787 Free PMC article. Updated. Preprint.
Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses.
Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V. Jeyachandran AV, et al. bioRxiv [Preprint]. 2023 Aug 5:2023.08.04.552083. doi: 10.1101/2023.08.04.552083. bioRxiv. 2023. PMID: 37577539 Free PMC article. Preprint.
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
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