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IGF-1 and bone: New discoveries from mouse models.
Yakar S, Courtland HW, Clemmons D. Yakar S, et al. J Bone Miner Res. 2010 Dec;25(12):2543-52. doi: 10.1002/jbmr.234. J Bone Miner Res. 2010. PMID: 20836088 Free PMC article. Review.
Reductions in serum IGF-1 during aging impair health span.
Gong Z, Kennedy O, Sun H, Wu Y, Williams GA, Klein L, Cardoso L, Matheny RW Jr, Hubbard GB, Ikeno Y, Farrar RP, Schaffler MB, Adamo ML, Muzumdar RH, Yakar S. Gong Z, et al. Aging Cell. 2014 Jun;13(3):408-18. doi: 10.1111/acel.12188. Epub 2013 Dec 30. Aging Cell. 2014. PMID: 24341939 Free PMC article.
Unbound (bioavailable) IGF1 enhances somatic growth.
Elis S, Wu Y, Courtland HW, Cannata D, Sun H, Beth-On M, Liu C, Jasper H, Domené H, Karabatas L, Guida C, Basta-Pljakic J, Cardoso L, Rosen CJ, Frystyk J, Yakar S. Elis S, et al. Dis Model Mech. 2011 Sep;4(5):649-58. doi: 10.1242/dmm.006775. Epub 2011 May 31. Dis Model Mech. 2011. PMID: 21628395 Free PMC article.
27 results