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β-Catenin signaling in hepatocellular carcinoma.
Xu C, Xu Z, Zhang Y, Evert M, Calvisi DF, Chen X. Xu C, et al. J Clin Invest. 2022 Feb 15;132(4):e154515. doi: 10.1172/JCI154515. J Clin Invest. 2022. PMID: 35166233 Free PMC article. Review.
Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver.
Fan W, Adebowale K, Váncza L, Li Y, Rabbi MF, Kunimoto K, Chen D, Mozes G, Chiu DK, Li Y, Tao J, Wei Y, Adeniji N, Brunsing RL, Dhanasekaran R, Singhi A, Geller D, Lo SH, Hodgson L, Engleman EG, Charville GW, Charu V, Monga SP, Kim T, Wells RG, Chaudhuri O, Török NJ. Fan W, et al. Nature. 2024 Feb;626(7999):635-642. doi: 10.1038/s41586-023-06991-9. Epub 2024 Jan 31. Nature. 2024. PMID: 38297127 Free PMC article.
β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.
Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A. Ruiz de Galarreta M, et al. Cancer Discov. 2019 Aug;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. Epub 2019 Jun 11. Cancer Discov. 2019. PMID: 31186238 Free PMC article.
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.
Wang H, Zhang S, Zhang Y, Jia J, Wang J, Liu X, Zhang J, Song X, Ribback S, Cigliano A, Evert M, Liang B, Wu H, Calvisi DF, Zeng Y, Chen X. Wang H, et al. J Hepatol. 2022 Jan;76(1):123-134. doi: 10.1016/j.jhep.2021.08.021. Epub 2021 Aug 28. J Hepatol. 2022. PMID: 34464659 Free PMC article.
Therapeutic efficacy of FASN inhibition in preclinical models of HCC.
Wang H, Zhou Y, Xu H, Wang X, Zhang Y, Shang R, O'Farrell M, Roessler S, Sticht C, Stahl A, Evert M, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Hepatology. 2022 Oct;76(4):951-966. doi: 10.1002/hep.32359. Epub 2022 Feb 16. Hepatology. 2022. PMID: 35076948 Free PMC article.
β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.
Zhang Y, Xu H, Cui G, Liang B, Chen X, Ko S, Affo S, Song X, Liao Y, Feng J, Wang P, Wang H, Xu M, Wang J, Pes GM, Ribback S, Zeng Y, Singhi A, Schwabe RF, Monga SP, Evert M, Tang L, Calvisi DF, Chen X. Zhang Y, et al. Gastroenterology. 2022 Aug;163(2):481-494. doi: 10.1053/j.gastro.2022.04.028. Epub 2022 Apr 27. Gastroenterology. 2022. PMID: 35489428 Free PMC article.
70 results