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2020 4
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Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Flanagan DJ, Amirkhah R, Vincent DF, Gunduz N, Gentaz P, Cammareri P, McCooey AJ, McCorry AMB, Fisher NC, Davis HL, Ridgway RA, Lohuis J, Leach JDG, Jackstadt R, Gilroy K, Mariella E, Nixon C, Clark W, Hedley A, Markert EK, Strathdee D, Bartholin L, Redmond KL, Kerr EM, Longley DB, Ginty F, Cho S, Coleman HG, Loughrey MB, Bardelli A, Maughan TS, Campbell AD, Lawler M, Leedham SJ, Barry ST, Inman GJ, van Rheenen J, Dunne PD, Sansom OJ. Flanagan DJ, et al. Nat Commun. 2022 Dec 7;13(1):7551. doi: 10.1038/s41467-022-35134-3. Nat Commun. 2022. PMID: 36477656 Free PMC article.
The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View.
Xavier JB, Young VB, Skufca J, Ginty F, Testerman T, Pearson AT, Macklin P, Mitchell A, Shmulevich I, Xie L, Caporaso JG, Crandall KA, Simone NL, Godoy-Vitorino F, Griffin TJ, Whiteson KL, Gustafson HH, Slade DJ, Schmidt TM, Walther-Antonio MRS, Korem T, Webb-Robertson BM, Styczynski MP, Johnson WE, Jobin C, Ridlon JM, Koh AY, Yu M, Kelly L, Wargo JA. Xavier JB, et al. Trends Cancer. 2020 Mar;6(3):192-204. doi: 10.1016/j.trecan.2020.01.004. Epub 2020 Feb 7. Trends Cancer. 2020. PMID: 32101723 Free PMC article. Review.
FLINO: a new method for immunofluorescence bioimage normalization.
Graf J, Cho S, McDonough E, Corwin A, Sood A, Lindner A, Salvucci M, Stachtea X, Van Schaeybroeck S, Dunne PD, Laurent-Puig P, Longley D, Prehn JHM, Ginty F. Graf J, et al. Bioinformatics. 2022 Jan 3;38(2):520-526. doi: 10.1093/bioinformatics/btab686. Bioinformatics. 2022. PMID: 34601553 Free PMC article.
Identification of unique rectal cancer-specific subtypes.
Kisakol B, Matveeva A, Salvucci M, Kel A, McDonough E, Ginty F, Longley DB, Prehn JHM. Kisakol B, et al. Br J Cancer. 2024 May;130(11):1809-1818. doi: 10.1038/s41416-024-02656-0. Epub 2024 Mar 26. Br J Cancer. 2024. PMID: 38532103 Free PMC article.
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution.
Lindner AU, Salvucci M, McDonough E, Cho S, Stachtea X, O'Connell EP, Corwin AD, Santamaria-Pang A, Carberry S, Fichtner M, Van Schaeybroeck S, Laurent-Puig P, Burke JP, McNamara DA, Lawler M, Sood A, Graf JF, Rehm M, Dunne PD, Longley DB, Ginty F, Prehn JHM. Lindner AU, et al. Cell Death Differ. 2022 Apr;29(4):806-817. doi: 10.1038/s41418-021-00895-9. Epub 2021 Nov 9. Cell Death Differ. 2022. PMID: 34754079 Free PMC article.
Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome.
Duggan WP, Salvucci M, Kisakol B, Lindner AU, Reynolds IS, Dussmann H, Fay J, O'Grady T, Longley DB, Ginty F, Mc Donough E, Slade DJ, Burke JP, Prehn JHM. Duggan WP, et al. J Mol Med (Berl). 2023 Jul;101(7):829-841. doi: 10.1007/s00109-023-02324-5. Epub 2023 May 12. J Mol Med (Berl). 2023. PMID: 37171483 Free PMC article.
National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions.
Kagan J, Moritz RL, Mazurchuk R, Lee JH, Kharchenko PV, Rozenblatt-Rosen O, Ruppin E, Edfors F, Ginty F, Goltsev Y, Wells JA, LaCava J, Riesterer JL, Germain RN, Shi T, Chee MS, Budnik BA, Yates JR 3rd, Chait BT, Moffitt JR, Smith RD, Srivastava S. Kagan J, et al. J Proteome Res. 2020 May 1;19(5):1900-1912. doi: 10.1021/acs.jproteome.0c00021. Epub 2020 Apr 2. J Proteome Res. 2020. PMID: 32163288
14 results