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Page 1
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
Cluntun AA, Badolia R, Lettlova S, Parnell KM, Shankar TS, Diakos NA, Olson KA, Taleb I, Tatum SM, Berg JA, Cunningham CN, Van Ry T, Bott AJ, Krokidi AT, Fogarty S, Skedros S, Swiatek WI, Yu X, Luo B, Merx S, Navankasattusas S, Cox JE, Ducker GS, Holland WL, McKellar SH, Rutter J, Drakos SG. Cluntun AA, et al. Cell Metab. 2021 Mar 2;33(3):629-648.e10. doi: 10.1016/j.cmet.2020.12.003. Epub 2020 Dec 16. Cell Metab. 2021. PMID: 33333007 Free PMC article.
Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk.
Li Y, Chaurasia B, Rahman MM, Kaddai V, Maschek JA, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, Meikle PJ, Atkinson D, Wang L, Poss AM, Playdon MC, Tippetts TS, Mousa EM, Nittayaboon K, Anandh Babu PV, Drummond MJ, Clevers H, Shayman JA, Hirabayashi Y, Holland WL, Rutter J, Edgar BA, Summers SA. Li Y, et al. Gastroenterology. 2023 Nov;165(5):1136-1150. doi: 10.1053/j.gastro.2023.07.017. Epub 2023 Aug 2. Gastroenterology. 2023. PMID: 37541526
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Bensard CL, Wisidagama DR, Olson KA, Berg JA, Krah NM, Schell JC, Nowinski SM, Fogarty S, Bott AJ, Wei P, Dove KK, Tanner JM, Panic V, Cluntun A, Lettlova S, Earl CS, Namnath DF, Vázquez-Arreguín K, Villanueva CJ, Tantin D, Murtaugh LC, Evason KJ, Ducker GS, Thummel CS, Rutter J. Bensard CL, et al. Cell Metab. 2020 Feb 4;31(2):284-300.e7. doi: 10.1016/j.cmet.2019.11.002. Epub 2019 Dec 5. Cell Metab. 2020. PMID: 31813825 Free PMC article.
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.
Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Brothwell MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. Siripoksup P, et al. J Clin Invest. 2024 Apr 23;134(11):e167371. doi: 10.1172/JCI167371. J Clin Invest. 2024. PMID: 38652544 Free PMC article.
17 results