R01 CA232347/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	1
2020	5
2021	3
2022	1
2023	7
2024	3

1

Epinephrine promotes breast cancer metastasis through a ubiquitin-specific peptidase 22-mediated lipolysis circuit.

Zhou Y, Chu P, Wang Y, Li N, Gao Q, Wang S, Wei J, Xue G, Zhao Y, Jia H, Song J, Zhang Y, Pang Y, Zhu H, Sun J, Ma S, Su C, Hu B, Zhao Z, Zhang H, Lu J, Wang J, Wang H, Sun Z, Fang D. Zhou Y, et al. Sci Adv. 2024 Aug 16;10(33):eado1533. doi: 10.1126/sciadv.ado1533. Epub 2024 Aug 16. Sci Adv. 2024. PMID: 39151008 Free PMC article.

2

CRISPR screen in regulatory T cells reveals modulators of Foxp3.

Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, Prator GY, Zhang B, Lee Y, Sun Z, Ifergan I, Van Gool F, Hargreaves DC, Bluestone JA, Marson A, Fang D. Cortez JT, et al. Nature. 2020 Jun;582(7812):416-420. doi: 10.1038/s41586-020-2246-4. Epub 2020 Apr 29. Nature. 2020. PMID: 32499641 Free PMC article.

3

CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.

Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D. Wang S, et al. J Clin Invest. 2023 Dec 1;133(23):e167728. doi: 10.1172/JCI167728. J Clin Invest. 2023. PMID: 38038129 Free PMC article.

4

scRNA-Seq and imaging mass cytometry analyses unveil iNKT cells-mediated anti-tumor immunity in pancreatic cancer liver metastasis.

Yi Q, Wang J, Liu T, Yao Y, Loveless I, Subedi K, Toor J, Adrianto I, Xiao H, Chen B, Crawford HC, Fang D, Zhou L, Mi QS. Yi Q, et al. Cancer Lett. 2023 May 1;561:216149. doi: 10.1016/j.canlet.2023.216149. Epub 2023 Mar 27. Cancer Lett. 2023. PMID: 36990268

5

HRD1-mediated METTL14 degradation regulates m⁶A mRNA modification to suppress ER proteotoxic liver disease.

Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D. Wei J, et al. Mol Cell. 2021 Dec 16;81(24):5052-5065.e6. doi: 10.1016/j.molcel.2021.10.028. Epub 2021 Nov 29. Mol Cell. 2021. PMID: 34847358 Free PMC article.

6

ATXN3 deubiquitinates YAP1 to promote tumor growth.

Wang S, Liu K, Han X, Cheng Y, Zhao E, Brat DJ, Sun Z, Fang D. Wang S, et al. Am J Cancer Res. 2023 Sep 15;13(9):4222-4234. eCollection 2023. Am J Cancer Res. 2023. PMID: 37818078 Free PMC article.

7

Endoplasmic Reticulum Protein Quality Control in β Cells.

Shrestha N, Reinert RB, Qi L. Shrestha N, et al. Semin Cell Dev Biol. 2020 Jul;103:59-67. doi: 10.1016/j.semcdb.2020.04.006. Epub 2020 May 8. Semin Cell Dev Biol. 2020. PMID: 32402517 Free PMC article. Review.

8

Endoplasmic reticulum-associated degradation and beyond: The multitasking roles for HRD1 in immune regulation and autoimmunity.

Xu Y, Fang D. Xu Y, et al. J Autoimmun. 2020 May;109:102423. doi: 10.1016/j.jaut.2020.102423. Epub 2020 Feb 11. J Autoimmun. 2020. PMID: 32057541 Free PMC article. Review.

9

Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.

Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, Huang YM, Zhang K, Shah YM, Sun S. Thepsuwan P, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2212644120. doi: 10.1073/pnas.2212644120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595688 Free PMC article.

10

HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination.

Wei J, Chen L, Li F, Yuan Y, Wang Y, Xia W, Zhang Y, Xu Y, Yang Z, Gao B, Jin C, Melo-Cardenas J, Green RM, Pan H, Wang J, He F, Zhang K, Fang D. Wei J, et al. EMBO J. 2018 Nov 15;37(22):e98942. doi: 10.15252/embj.201898942. Epub 2018 Nov 2. EMBO J. 2018. PMID: 30389664 Free PMC article.

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