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Amphipathic Liponecrosis Impairs Bacterial Clearance and Causes Infection During Sterile Inflammation.
Kostenko S, Khatua B, Trivedi S, Pillai AN, McFayden B, Morsy M, Rajalingamgari P, Sharma V, Noel P, Patel K, El-Kurdi B, Borges da Silva H, Chen X, Chandan V, Navina S, Vela S, Cartin-Ceba R, Snozek C, Singh VP. Kostenko S, et al. Gastroenterology. 2023 Oct;165(4):999-1015. doi: 10.1053/j.gastro.2023.05.034. Epub 2023 May 30. Gastroenterology. 2023. PMID: 37263302 Free PMC article.
NSAIDs do not reduce severity among post-ERCP pancreatitis patients.
El Kurdi B, Imam Z, Abonofal A, Babar S, Shah P, Pannala R, Papachristou G, Echavarria J, Pisipati S, Jahangir S, Rajalingamgari P, Chang YH, Singh VP. El Kurdi B, et al. Pancreatology. 2024 Feb;24(1):14-23. doi: 10.1016/j.pan.2023.11.003. Epub 2023 Nov 2. Pancreatology. 2024. PMID: 37981523
Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation.
de Oliveira C, Khatua B, Noel P, Kostenko S, Bag A, Balakrishnan B, Patel KS, Guerra AA, Martinez MN, Trivedi S, McCullough A, Lam-Himlin DM, Navina S, Faigel DO, Fukami N, Pannala R, Phillips AE, Papachristou GI, Kershaw EE, Lowe ME, Singh VP. de Oliveira C, et al. J Clin Invest. 2020 Apr 1;130(4):1931-1947. doi: 10.1172/JCI132767. J Clin Invest. 2020. PMID: 31917686 Free PMC article. Clinical Trial.
Evidence showing lipotoxicity worsens outcomes in covid-19 patients and insights about the underlying mechanisms.
Cartin-Ceba R, Khatua B, El-Kurdi B, Trivedi S, Kostenko S, Imam Z, Smith R, Snozek C, Navina S, Sharma V, McFayden B, Ionescu F, Stolow E, Keiser S, Tejani A, Harrington A, Acosta P, Kuwelker S, Echavarria J, Nair GB, Bataineh A, Singh VP. Cartin-Ceba R, et al. iScience. 2022 May 20;25(5):104322. doi: 10.1016/j.isci.2022.104322. Epub 2022 Apr 27. iScience. 2022. PMID: 35502320 Free PMC article.
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