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Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC. Deja S, et al. Cell Metab. 2024 May 7;36(5):1088-1104.e12. doi: 10.1016/j.cmet.2024.02.004. Epub 2024 Mar 5. Cell Metab. 2024. PMID: 38447582 Free article.
Krebs takes a turn at cell differentiation.
Deja S, Crawford PA, Burgess SC. Deja S, et al. Cell Metab. 2022 May 3;34(5):658-660. doi: 10.1016/j.cmet.2022.04.005. Cell Metab. 2022. PMID: 35508108 Free article.
Measurement of lipogenic flux by deuterium resolved mass spectrometry.
Fu X, Deja S, Fletcher JA, Anderson NN, Mizerska M, Vale G, Browning JD, Horton JD, McDonald JG, Mitsche MA, Burgess SC. Fu X, et al. Nat Commun. 2021 Jun 18;12(1):3756. doi: 10.1038/s41467-021-23958-4. Nat Commun. 2021. PMID: 34145255 Free PMC article.
12 results