R01 GM038213/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1993	1
1994	1
1998	3
1999	3
2000	2
2001	3
2002	4
2003	2
2004	4
2005	1
2006	4
2007	2
2008	3
2009	4
2010	8
2011	3
2012	2
2013	3
2014	1
2015	2
2016	1
2024	0

1

Molecular pharmacology, physiology, and structure of the P2Y receptors.

von Kügelgen I, Harden TK. von Kügelgen I, et al. Adv Pharmacol. 2011;61:373-415. doi: 10.1016/B978-0-12-385526-8.00012-6. Adv Pharmacol. 2011. PMID: 21586365 Review.

2

Signalling and pharmacological properties of the P2Y receptor.

Harden TK, Sesma JI, Fricks IP, Lazarowski ER. Harden TK, et al. Acta Physiol (Oxf). 2010 Jun;199(2):149-60. doi: 10.1111/j.1748-1716.2010.02116.x. Epub 2010 Mar 24. Acta Physiol (Oxf). 2010. PMID: 20345417 Free PMC article. Review.

3

UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.

Lazarowski ER, Harden TK. Lazarowski ER, et al. Mol Pharmacol. 2015 Jul;88(1):151-60. doi: 10.1124/mol.115.098756. Epub 2015 Mar 31. Mol Pharmacol. 2015. PMID: 25829059 Free PMC article. Review.

4

Development of selective high affinity antagonists, agonists, and radioligands for the P2Y1 receptor.

Houston D, Costanzi S, Jacobson KA, Harden TK. Houston D, et al. Comb Chem High Throughput Screen. 2008 Jul;11(6):410-9. doi: 10.2174/138620708784911474. Comb Chem High Throughput Screen. 2008. PMID: 18673269 Free PMC article. Review.

5

UDP-glucose promotes neutrophil recruitment in the lung.

Sesma JI, Weitzer CD, Livraghi-Butrico A, Dang H, Donaldson S, Alexis NE, Jacobson KA, Harden TK, Lazarowski ER. Sesma JI, et al. Purinergic Signal. 2016 Dec;12(4):627-635. doi: 10.1007/s11302-016-9524-5. Epub 2016 Jul 15. Purinergic Signal. 2016. PMID: 27421735 Free PMC article.

6

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.

Ko H, Carter RL, Cosyn L, Petrelli R, de Castro S, Besada P, Zhou Y, Cappellacci L, Franchetti P, Grifantini M, Van Calenbergh S, Harden TK, Jacobson KA. Ko H, et al. Bioorg Med Chem. 2008 Jun 15;16(12):6319-32. doi: 10.1016/j.bmc.2008.05.013. Epub 2008 May 9. Bioorg Med Chem. 2008. PMID: 18514530 Free PMC article.

7

Quantitation of extracellular UTP using a sensitive enzymatic assay.

Lazarowski ER, Harden TK. Lazarowski ER, et al. Br J Pharmacol. 1999 Jul;127(5):1272-8. doi: 10.1038/sj.bjp.0702654. Br J Pharmacol. 1999. PMID: 10455275 Free PMC article.

8

Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors.

Jacobson KA, Costanzi S, Ivanov AA, Tchilibon S, Besada P, Gao ZG, Maddileti S, Harden TK. Jacobson KA, et al. Biochem Pharmacol. 2006 Feb 14;71(4):540-9. doi: 10.1016/j.bcp.2005.11.010. Epub 2005 Dec 15. Biochem Pharmacol. 2006. PMID: 16359641 Free PMC article.

9

Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor.

Kiselev E, Balasubramanian R, Uliassi E, Brown KA, Trujillo K, Katritch V, Hammes E, Stevens RC, Harden TK, Jacobson KA. Kiselev E, et al. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4733-4739. doi: 10.1016/j.bmcl.2015.08.021. Epub 2015 Aug 10. Bioorg Med Chem Lett. 2015. PMID: 26303895 Free PMC article.

10

Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor.

Carter RL, Fricks IP, Barrett MO, Burianek LE, Zhou Y, Ko H, Das A, Jacobson KA, Lazarowski ER, Harden TK. Carter RL, et al. Mol Pharmacol. 2009 Dec;76(6):1341-8. doi: 10.1124/mol.109.058578. Epub 2009 Sep 16. Mol Pharmacol. 2009. PMID: 19759354 Free PMC article.

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