R01 GM103853/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2012	1
2013	4
2014	4
2015	1
2016	2
2018	2
2019	1
2020	3
2021	3
2022	3
2023	9
2024	2

1

Metabolomic, Proteomic, and Single-Cell Proteomic Analysis of Cancer Cells Treated with the KRAS^G12D Inhibitor MRTX1133.

Orsburn BC. Orsburn BC. J Proteome Res. 2023 Dec 1;22(12):3703-3713. doi: 10.1021/acs.jproteome.3c00212. Epub 2023 Nov 20. J Proteome Res. 2023. PMID: 37983312 Free PMC article.

2

Pharmacogenomics of Antiretroviral Drug Metabolism and Transport.

Yu ZJ, Mosher EP, Bumpus NN. Yu ZJ, et al. Annu Rev Pharmacol Toxicol. 2021 Jan 6;61:565-585. doi: 10.1146/annurev-pharmtox-021320-111248. Epub 2020 Sep 22. Annu Rev Pharmacol Toxicol. 2021. PMID: 32960701 Free PMC article. Review.

3

Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies.

Wheeler AM, Eberhard CD, Mosher EP, Yuan Y, Wilkins HN, Seneviratne HK, Orsburn BC, Bumpus NN. Wheeler AM, et al. Drug Metab Dispos. 2023 Mar;51(3):350-359. doi: 10.1124/dmd.122.001043. Epub 2023 Jan 10. Drug Metab Dispos. 2023. PMID: 36627162 Free PMC article. Review.

4

Biotransformation of Efavirenz and Proteomic Analysis of Cytochrome P450s and UDP-Glucuronosyltransferases in Mouse, Macaque, and Human Brain-Derived In Vitro Systems.

Wheeler AM, Orsburn BC, Bumpus NN. Wheeler AM, et al. Drug Metab Dispos. 2023 Apr;51(4):521-531. doi: 10.1124/dmd.122.001195. Epub 2023 Jan 9. Drug Metab Dispos. 2023. PMID: 36623884 Free PMC article.

5

Efavirenz and Efavirenz-like Compounds Activate Human, Murine, and Macaque Hepatic IRE1α-XBP1.

Heck CJS, Hamlin AN, Bumpus NN. Heck CJS, et al. Mol Pharmacol. 2019 Feb;95(2):183-195. doi: 10.1124/mol.118.113647. Epub 2018 Nov 15. Mol Pharmacol. 2019. PMID: 30442673 Free PMC article.

6

EstG is a novel esterase required for cell envelope integrity in Caulobacter.

Daitch AK, Orsburn BC, Chen Z, Alvarez L, Eberhard CD, Sundararajan K, Zeinert R, Kreitler DF, Jakoncic J, Chien P, Cava F, Gabelli SB, Goley ED. Daitch AK, et al. Curr Biol. 2023 Jan 23;33(2):228-240.e7. doi: 10.1016/j.cub.2022.11.037. Epub 2022 Dec 13. Curr Biol. 2023. PMID: 36516849 Free PMC article.

7

Time-of-Flight Fragmentation Spectra Generated by the Proteomic Analysis of Single Human Cells Do Not Exhibit Atypical Fragmentation Patterns.

Orsburn BC. Orsburn BC. J Proteome Res. 2023 Mar 3;22(3):1003-1008. doi: 10.1021/acs.jproteome.2c00715. Epub 2023 Jan 26. J Proteome Res. 2023. PMID: 36700448 Free PMC article.

8

Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites.

Lee JH, Mosher EP, Lee YS, Bumpus NN, Berger JM. Lee JH, et al. Cell Chem Biol. 2022 Mar 17;29(3):476-489.e6. doi: 10.1016/j.chembiol.2021.08.014. Epub 2021 Sep 15. Cell Chem Biol. 2022. PMID: 34529934 Free PMC article.

9

A targeted proteomics approach for profiling murine cytochrome P450 expression.

Hersman EM, Bumpus NN. Hersman EM, et al. J Pharmacol Exp Ther. 2014 May;349(2):221-8. doi: 10.1124/jpet.113.212456. Epub 2014 Mar 4. J Pharmacol Exp Ther. 2014. PMID: 24594750 Free PMC article.

10

Metabolomic, proteomic and single cell proteomic analysis of cancer cells treated with the KRAS^G12D inhibitor MRTX1133.

Orsburn BC. Orsburn BC. bioRxiv [Preprint]. 2023 Sep 13:2023.03.23.533981. doi: 10.1101/2023.03.23.533981. bioRxiv. 2023. Update in: J Proteome Res. 2023 Dec 1;22(12):3703-3713. doi: 10.1021/acs.jproteome.3c00212. PMID: 36993160 Free PMC article. Updated. Preprint.

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