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Sequence determinants of improved CRISPR sgRNA design.
Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Xu H, et al. Genome Res. 2015 Aug;25(8):1147-57. doi: 10.1101/gr.191452.115. Epub 2015 Jun 10. Genome Res. 2015. PMID: 26063738 Free PMC article.
Deciphering essential cistromes using genome-wide CRISPR screens.
Fei T, Li W, Peng J, Xiao T, Chen CH, Wu A, Huang J, Zang C, Liu XS, Brown M. Fei T, et al. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25186-25195. doi: 10.1073/pnas.1908155116. Epub 2019 Nov 14. Proc Natl Acad Sci U S A. 2019. PMID: 31727847 Free PMC article.
Improved design and analysis of CRISPR knockout screens.
Chen CH, Xiao T, Xu H, Jiang P, Meyer CA, Li W, Brown M, Liu XS. Chen CH, et al. Bioinformatics. 2018 Dec 1;34(23):4095-4101. doi: 10.1093/bioinformatics/bty450. Bioinformatics. 2018. PMID: 29868757 Free PMC article.
CRISPR-DO for genome-wide CRISPR design and optimization.
Ma J, Köster J, Qin Q, Hu S, Li W, Chen C, Cao Q, Wang J, Mei S, Liu Q, Xu H, Liu XS. Ma J, et al. Bioinformatics. 2016 Nov 1;32(21):3336-3338. doi: 10.1093/bioinformatics/btw476. Epub 2016 Jul 10. Bioinformatics. 2016. PMID: 27402906 Free PMC article.
PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.
Spangle JM, Dreijerink KM, Groner AC, Cheng H, Ohlson CE, Reyes J, Lin CY, Bradner J, Zhao JJ, Roberts TM, Brown M. Spangle JM, et al. Cell Rep. 2016 Jun 21;15(12):2692-704. doi: 10.1016/j.celrep.2016.05.046. Epub 2016 Jun 9. Cell Rep. 2016. PMID: 27292631 Free PMC article.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
Xiao T, Li W, Wang X, Xu H, Yang J, Wu Q, Huang Y, Geradts J, Jiang P, Fei T, Chi D, Zang C, Liao Q, Rennhack J, Andrechek E, Li N, Detre S, Dowsett M, Jeselsohn RM, Liu XS, Brown M. Xiao T, et al. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7869-7878. doi: 10.1073/pnas.1722617115. Epub 2018 Jul 9. Proc Natl Acad Sci U S A. 2018. PMID: 29987050 Free PMC article.
11 results