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Page 1
Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction.
Hahn VS, Petucci C, Kim MS, Bedi KC Jr, Wang H, Mishra S, Koleini N, Yoo EJ, Margulies KB, Arany Z, Kelly DP, Kass DA, Sharma K. Hahn VS, et al. Circulation. 2023 Apr 11;147(15):1147-1161. doi: 10.1161/CIRCULATIONAHA.122.061846. Epub 2023 Mar 1. Circulation. 2023. PMID: 36856044 Free PMC article.
Ketolysis drives CD8+ T cell effector function through effects on histone acetylation.
Luda KM, Longo J, Kitchen-Goosen SM, Duimstra LR, Ma EH, Watson MJ, Oswald BM, Fu Z, Madaj Z, Kupai A, Dickson BM, DeCamp LM, Dahabieh MS, Compton SE, Teis R, Kaymak I, Lau KH, Kelly DP, Puchalska P, Williams KS, Krawczyk CM, Lévesque D, Boisvert FM, Sheldon RD, Rothbart SB, Crawford PA, Jones RG. Luda KM, et al. Immunity. 2023 Sep 12;56(9):2021-2035.e8. doi: 10.1016/j.immuni.2023.07.002. Epub 2023 Jul 28. Immunity. 2023. PMID: 37516105 Free PMC article.
Cardiac maturation.
Sakamoto T, Kelly DP. Sakamoto T, et al. J Mol Cell Cardiol. 2024 Feb;187:38-50. doi: 10.1016/j.yjmcc.2023.12.008. Epub 2023 Dec 30. J Mol Cell Cardiol. 2024. PMID: 38160640 Free article. Review.
Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy.
Previs MJ, O'Leary TS, Morley MP, Palmer BM, LeWinter M, Yob JM, Pagani FD, Petucci C, Kim MS, Margulies KB, Arany Z, Kelly DP, Day SM. Previs MJ, et al. Circ Heart Fail. 2022 Jun;15(6):e009521. doi: 10.1161/CIRCHEARTFAILURE.121.009521. Epub 2022 May 11. Circ Heart Fail. 2022. PMID: 35543134 Free PMC article.
Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction.
Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA, Yang H, Abilez OJ, Lyu X, Narayan SM, Mestroni L, Taylor MRG, Recchia FA, Wu JC. Tu C, et al. Nat Biomed Eng. 2024 Apr;8(4):479-494. doi: 10.1038/s41551-023-01134-x. Epub 2023 Nov 27. Nat Biomed Eng. 2024. PMID: 38012305 Free PMC article.
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function.
Dierickx P, Zhu K, Carpenter BJ, Jiang C, Vermunt MW, Xiao Y, Luongo TS, Yamamoto T, Martí-Pàmies Í, Mia S, Latimer M, Diwan A, Zhao J, Hauck AK, Krusen B, Nguyen HCB, Blobel GA, Kelly DP, Pei L, Baur JA, Young ME, Lazar MA. Dierickx P, et al. Nat Cardiovasc Res. 2022 Jan;1(1):45-58. doi: 10.1038/s44161-021-00001-9. Epub 2021 Dec 23. Nat Cardiovasc Res. 2022. PMID: 35036997 Free PMC article.
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