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Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.
Galarza-Muñoz G, Briggs FBS, Evsyukova I, Schott-Lerner G, Kennedy EM, Nyanhete T, Wang L, Bergamaschi L, Widen SG, Tomaras GD, Ko DC, Bradrick SS, Barcellos LF, Gregory SG, Garcia-Blanco MA. Galarza-Muñoz G, et al. Cell. 2017 Mar 23;169(1):72-84.e13. doi: 10.1016/j.cell.2017.03.007. Cell. 2017. PMID: 28340352 Free PMC article.
U2AF2 binds IL7R exon 6 ectopically and represses its inclusion.
Schott G, Galarza-Muñoz G, Trevino N, Chen X, Weirauch M, Gregory SG, Bradrick SS, Garcia-Blanco MA. Schott G, et al. RNA. 2021 Feb 10;27(5):571-83. doi: 10.1261/rna.078279.120. Online ahead of print. RNA. 2021. PMID: 33568552 Free PMC article.