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Iron chelators ICL670 and 311 inhibit HIV-1 transcription.
Debebe Z, Ammosova T, Jerebtsova M, Kurantsin-Mills J, Niu X, Charles S, Richardson DR, Ray PE, Gordeuk VR, Nekhai S. Debebe Z, et al. Virology. 2007 Oct 25;367(2):324-33. doi: 10.1016/j.virol.2007.06.011. Epub 2007 Jul 13. Virology. 2007. PMID: 17631934 Free PMC article.
Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration.
Charles S, Ammosova T, Cardenas J, Foster A, Rotimi J, Jerebtsova M, Ayodeji AA, Niu X, Ray PE, Gordeuk VR, Kashanchi F, Nekhai S. Charles S, et al. J Cell Physiol. 2009 Nov;221(2):469-79. doi: 10.1002/jcp.21882. J Cell Physiol. 2009. PMID: 19626680 Free PMC article.
Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9.
Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Debebe Z, et al. Mol Pharmacol. 2011 Jan;79(1):185-96. doi: 10.1124/mol.110.069062. Epub 2010 Oct 18. Mol Pharmacol. 2011. PMID: 20956357 Free PMC article.