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MEKK4 sequesters RIP2 to dictate NOD2 signal specificity.
Curr Biol. 2008 Sep 23;18(18):1402-8. doi: 10.1016/j.cub.2008.07.084. Epub 2008 Sep 4.
Curr Biol. 2008.
PMID: 18775659
Free PMC article.
A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.
Marinis JM, Homer CR, McDonald C, Abbott DW.
Marinis JM, et al.
J Biol Chem. 2011 Jan 21;286(3):1938-50. doi: 10.1074/jbc.M110.189308. Epub 2010 Nov 19.
J Biol Chem. 2011.
PMID: 21097508
Free PMC article.
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ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.
Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW.
Tao M, et al.
Curr Biol. 2009 Aug 11;19(15):1255-63. doi: 10.1016/j.cub.2009.06.038. Epub 2009 Jul 9.
Curr Biol. 2009.
PMID: 19592251
Free PMC article.
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