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Page 1
The biology of TREM receptors.
Colonna M. Colonna M. Nat Rev Immunol. 2023 Sep;23(9):580-594. doi: 10.1038/s41577-023-00837-1. Epub 2023 Feb 7. Nat Rev Immunol. 2023. PMID: 36750615 Free PMC article. Review.
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Molgora M, Esaulova E, Vermi W, Hou J, Chen Y, Luo J, Brioschi S, Bugatti M, Omodei AS, Ricci B, Fronick C, Panda SK, Takeuchi Y, Gubin MM, Faccio R, Cella M, Gilfillan S, Unanue ER, Artyomov MN, Schreiber RD, Colonna M. Molgora M, et al. Cell. 2020 Aug 20;182(4):886-900.e17. doi: 10.1016/j.cell.2020.07.013. Epub 2020 Aug 11. Cell. 2020. PMID: 32783918 Free PMC article.
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Ulland TK, Song WM, Huang SC, Ulrich JD, Sergushichev A, Beatty WL, Loboda AA, Zhou Y, Cairns NJ, Kambal A, Loginicheva E, Gilfillan S, Cella M, Virgin HW, Unanue ER, Wang Y, Artyomov MN, Holtzman DM, Colonna M. Ulland TK, et al. Cell. 2017 Aug 10;170(4):649-663.e13. doi: 10.1016/j.cell.2017.07.023. Cell. 2017. PMID: 28802038 Free PMC article.
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Zhou Y, Song WM, Andhey PS, Swain A, Levy T, Miller KR, Poliani PL, Cominelli M, Grover S, Gilfillan S, Cella M, Ulland TK, Zaitsev K, Miyashita A, Ikeuchi T, Sainouchi M, Kakita A, Bennett DA, Schneider JA, Nichols MR, Beausoleil SA, Ulrich JD, Holtzman DM, Artyomov MN, Colonna M. Zhou Y, et al. Nat Med. 2020 Jan;26(1):131-142. doi: 10.1038/s41591-019-0695-9. Epub 2020 Jan 13. Nat Med. 2020. PMID: 31932797 Free PMC article.
TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Wang S, Sudan R, Peng V, Zhou Y, Du S, Yuede CM, Lei T, Hou J, Cai Z, Cella M, Nguyen K, Poliani PL, Beatty WL, Chen Y, Cao S, Lin K, Rodrigues C, Ellebedy AH, Gilfillan S, Brown GD, Holtzman DM, Brioschi S, Colonna M. Wang S, et al. Cell. 2022 Oct 27;185(22):4153-4169.e19. doi: 10.1016/j.cell.2022.09.033. Cell. 2022. PMID: 36306735 Free PMC article.
Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination.
Hou J, Zhou Y, Cai Z, Terekhova M, Swain A, Andhey PS, Guimaraes RM, Ulezko Antonova A, Qiu T, Sviben S, Strout G, Fitzpatrick JAJ, Chen Y, Gilfillan S, Kim DH, Van Dyken SJ, Artyomov MN, Colonna M. Hou J, et al. Cell Rep. 2023 Apr 25;42(4):112293. doi: 10.1016/j.celrep.2023.112293. Epub 2023 Mar 21. Cell Rep. 2023. PMID: 36952346 Free PMC article.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
19 results