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HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.
Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S. Cui M, et al. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306454120. doi: 10.1073/pnas.2306454120. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170752 Free PMC article.
β cell acetate production and release are negligible.
Xu K, Nnyamah C, Pandya N, Sweis N, Corona-Avila I, Priyadarshini M, Wicksteed B, Layden BT. Xu K, et al. Islets. 2024 Dec 31;16(1):2339558. doi: 10.1080/19382014.2024.2339558. Epub 2024 Apr 12. Islets. 2024. PMID: 38607959 Free PMC article.
Development of an Acrylamide-Based Inhibitor of Protein S-Acylation.
Azizi SA, Lan T, Delalande C, Kathayat RS, Banales Mejia F, Qin A, Brookes N, Sandoval PJ, Dickinson BC. Azizi SA, et al. ACS Chem Biol. 2021 Aug 20;16(8):1546-1556. doi: 10.1021/acschembio.1c00405. Epub 2021 Jul 26. ACS Chem Biol. 2021. PMID: 34309372 Free PMC article.
24 results