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2021 4
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2024 8

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Page 1
In situ identification of cellular drug targets in mammalian tissue.
Pang Z, Schafroth MA, Ogasawara D, Wang Y, Nudell V, Lal NK, Yang D, Wang K, Herbst DM, Ha J, Guijas C, Blankman JL, Cravatt BF, Ye L. Pang Z, et al. Cell. 2022 May 12;185(10):1793-1805.e17. doi: 10.1016/j.cell.2022.03.040. Epub 2022 Apr 27. Cell. 2022. PMID: 35483372 Free PMC article.
The Sts Proteins: Modulators of Host Immunity.
Zaman A, French JB, Carpino N. Zaman A, et al. Int J Mol Sci. 2023 May 16;24(10):8834. doi: 10.3390/ijms24108834. Int J Mol Sci. 2023. PMID: 37240179 Free PMC article. Review.
Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Coant N, Bickel JD, Rahaim R, Otsuka Y, Choi YM, Xu R, Simoes M, Cariello C, Mao C, Saied EM, Arenz C, Spicer TP, Bannister TD, Tonge PJ, Airola MV, Scampavia L, Hannun YA, Rizzo RC, Haley JD. Coant N, et al. Bioorg Chem. 2023 Oct;139:106747. doi: 10.1016/j.bioorg.2023.106747. Epub 2023 Jul 27. Bioorg Chem. 2023. PMID: 37531819 Free PMC article.
In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma.
Rajan RG, Fernandez-Vega V, Sperry J, Nakashima J, Do LH, Andrews W, Boca S, Islam R, Chowdhary SA, Seldin J, Souza GR, Scampavia L, Hanafy KA, Vrionis FD, Spicer TP. Rajan RG, et al. Cancers (Basel). 2023 Jun 22;15(13):3289. doi: 10.3390/cancers15133289. Cancers (Basel). 2023. PMID: 37444398 Free PMC article.
Target-based discovery of a broad-spectrum flukicide.
Sprague DJ, Park SK, Gramberg S, Bauer L, Rohr CM, Chulkov EG, Smith E, Scampavia L, Spicer TP, Haeberlein S, Marchant JS. Sprague DJ, et al. Nat Struct Mol Biol. 2024 Sep;31(9):1386-1393. doi: 10.1038/s41594-024-01298-3. Epub 2024 May 7. Nat Struct Mol Biol. 2024. PMID: 38714890
Identification of Potential Modulators of the RGS7/Gβ5/R7BP Complex.
Stoveken HM, Fernandez-Vega V, Muntean BS, Patil DN, Shumate J, Bannister TD, Scampavia L, Spicer TP, Martemyanov KA. Stoveken HM, et al. SLAS Discov. 2021 Oct;26(9):1177-1188. doi: 10.1177/24725552211020679. Epub 2021 Jun 11. SLAS Discov. 2021. PMID: 34112017 Free PMC article.
High throughput screening for SARS-CoV-2 helicase inhibitors.
Otsuka Y, Kim E, Krueger A, Shumate J, Wang C, Bdiri B, Ullah S, Park H, Scampavia L, Bannister TD, Chung D, Spicer TP. Otsuka Y, et al. SLAS Discov. 2024 Sep;29(6):100180. doi: 10.1016/j.slasd.2024.100180. Epub 2024 Aug 22. SLAS Discov. 2024. PMID: 39173831 Free article.
Identification of potent small molecule inhibitors of SARS-CoV-2 entry.
Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Liu Z, Chen K, Dai J, Xu P, Sun W, Liu W, Zhao Z, Bennett SP, Li P, Ma T, Lin Y, Kawakami A, Yu J, Wang F, Wang C, Li M, Chase P, Hodder P, Spicer TP, Scampavia L, Cao C, Pan L, Dong J, Chen Y, Yu B, Guo M, Fang P, Fisher DE, Wang J. Liu Z, et al. Cell Res. 2023 Jan;33(1):55-70. doi: 10.1038/s41422-022-00744-5. Epub 2023 Jan 2. Cell Res. 2023. PMID: 36588115 Free PMC article.
27 results